3-(Pyrrolidin-2-ylmethyl)pyridine

Base Information

Chemical Name:3-(Pyrrolidin-2-ylmethyl)pyridine
CAS No.:106366-28-3
Molecular Formula:C10H14N2
Molecular Weight:162.23
Hs Code.:
European Community (EC) Number:842-283-0
DSSTox Substance ID:DTXSID501302874
Mol file:106366-28-3.mol

Synonyms:3-(pyrrolidin-2-ylmethyl)pyridine;106366-28-3;3-PYRROLIDIN-2-YLMETHYL-PYRIDINE;3-[(pyrrolidin-2-yl)methyl]pyridine;3-(2-Pyrrolidinylmethyl)pyridine;SCHEMBL2981954;GFYJSFUVPAUKJA-UHFFFAOYSA-N;DTXSID501302874;AKOS006230104;FT-0726400;EN300-1238584

Suppliers and Price of 3-(Pyrrolidin-2-ylmethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-PYRROLIDIN-2-YLMETHYLPYRIDINE 95.00%
5MG
$ 499.39

AK Scientific
3-(Pyrrolidin-2-ylmethyl)pyridine
10g
$ 6235.00

AK Scientific
3-(Pyrrolidin-2-ylmethyl)pyridine
5g
$ 4236.00

AK Scientific
3-(Pyrrolidin-2-ylmethyl)pyridine
25mg
$ 334.00

AK Scientific
3-(Pyrrolidin-2-ylmethyl)pyridine
2mg
$ 218.00

Total 1 raw suppliers

Chemical Property of 3-(Pyrrolidin-2-ylmethyl)pyridine

Chemical Property:

Melting Point:128-129℃
Boiling Point:274℃
PKA:10.33±0.10(Predicted)
Flash Point:120℃
PSA：24.92000
Density:1.038
LogP:1.70490
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:162.115698455
Heavy Atom Count:12
Complexity:136

Purity/Quality:: 3-PYRROLIDIN-2-YLMETHYLPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)CC2=CN=CC=C2

Technology Process of 3-(Pyrrolidin-2-ylmethyl)pyridine

There total 3 articles about 3-(Pyrrolidin-2-ylmethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.4%

: 106366-21-6
2-(3-pyridylmethyl)-1-pyrroline

: 106366-28-3
(R,S)-2-(3-pyridylmethyl)pyrrolidine

Guidance literature:: With hydrogenchloride; sodium cyanoborohydride; In methanol; for 10h;

Reference yield:

: 39931-77-6
pyridin-3-yl-acetic acid ethyl ester

: 106366-28-3
(R,S)-2-(3-pyridylmethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) ether, hexane, -70 deg C, 15 min, 2.) ether, hexane, from -70 deg C to RT, 20 h

2: 84.1 percent / aq. HCl / 20 h / Heating

3: 89.4 percent / NaCNBH₃, aq. HCl / methanol / 10 h

With hydrogenchloride; sodium cyanoborohydride; lithium diisopropyl amide; In methanol;

Reference yield:

: 106366-34-1
(R,S)-3-(3-pyridylacetyl)-2-pyrrolidinone

: 106366-28-3
(R,S)-2-(3-pyridylmethyl)pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 84.1 percent / aq. HCl / 20 h / Heating

2: 89.4 percent / NaCNBH₃, aq. HCl / methanol / 10 h

With hydrogenchloride; sodium cyanoborohydride; In methanol;