Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate

Base Information

Chemical Name:Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate
CAS No.:894779-28-3
Molecular Formula:C12H12O4
Molecular Weight:220.225
Hs Code.:2932999099
DSSTox Substance ID:DTXSID00467856
Wikidata:Q82294930
Mol file:894779-28-3.mol

Synonyms:894779-28-3;ETHYL 4-HYDROXY-2-METHYLBENZOFURAN-6-CARBOXYLATE;ethyl 4-hydroxy-2-methyl-1-benzofuran-6-carboxylate;ethyl4-hydroxy-2-methylbenzofuran-6-carboxylate;SCHEMBL644235;DTXSID00467856;FUMIJABWOZOAAU-UHFFFAOYSA-N;AKOS027338812;AS-67856;CS-0172306;A922505;A1-03849

Suppliers and Price of Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate 95%
5g
$ 1663.00

Crysdot
Ethyl4-hydroxy-2-methylbenzofuran-6-carboxylate 97%
1g
$ 492.00

Alichem
Ethyl4-hydroxy-2-methyl-1-benzofuran-6-carboxylate
5g
$ 1856.38

Alichem
Ethyl4-hydroxy-2-methyl-1-benzofuran-6-carboxylate
250mg
$ 264.60

Alichem
Ethyl4-hydroxy-2-methyl-1-benzofuran-6-carboxylate
1g
$ 625.26

AK Scientific
Ethyl4-hydroxy-2-methylbenzofuran-6-carboxylate
1g
$ 902.00

A1 Biochem Labs
Ethyl4-hydroxy-2-methylbenzofuran-6-carboxylate 95%
5 g
$ 950.00

Total 3 raw suppliers

Chemical Property of Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate

Chemical Property:

Melting Point:89-92 °C
Boiling Point:248.8±15.0 °C(Predicted)
PKA:8.44±0.40(Predicted)
PSA：59.67000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:2.62350
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.07355886
Heavy Atom Count:16
Complexity:266

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C2C=C(OC2=C1)C)O

Technology Process of Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate

There total 3 articles about Ethyl 4-hydroxy-2-methylbenzofuran-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 955886-29-0
ethyl 4-(acetyloxy)-2-methyl-1-benzofuran-6-carboxylate

: 894779-28-3
4-hydroxy-2-methylbenzofuran-6-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In ethanol; hexane; dichloromethane; toluene;

Reference yield: 65.0%

: 74-99-7
prop-1-yne

: 692204-84-5
ethyl 4-iodo-3,5-dihydroxybenzoate

: 894779-28-3
4-hydroxy-2-methylbenzofuran-6-carboxylic acid ethyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine; In 1,2-dimethoxyethane;
DOI:10.1021/op900263b

Reference yield:

: 2-[1-(5-Methyl-furan-2-yl)-meth-(E)-ylidene]-succinic acid 1-ethyl ester

: 894779-28-3
4-hydroxy-2-methylbenzofuran-6-carboxylic acid ethyl ester

Guidance literature:: 2-[1-(5-Methyl-furan-2-yl)-meth-(E)-ylidene]-succinic acid 1-ethyl ester; With sodium acetate; acetic anhydride; for 5h; Heating;

With potassium carbonate; In ethanol; for 18h; Heating;
DOI:10.1021/jm0510732