5-amino-2,2-dimethyl-2H-pyran-3(6H)-one

Base Information

Chemical Name:5-amino-2,2-dimethyl-2H-pyran-3(6H)-one
CAS No.:372120-56-4
Molecular Formula:C₇H₁₁NO₂
Molecular Weight:141.17
Hs Code.:
DSSTox Substance ID:DTXSID601278054
Mol file:372120-56-4.mol

Synonyms:372120-56-4;5-amino-2,2-dimethyl-2H-pyran-3(6H)-one;SCHEMBL6023669;NDNONHJANFHZKC-UHFFFAOYSA-N;DTXSID601278054;AKOS006365552;DB-270438;2H-Pyran-3(6H)-one, 5-amino-2,2-dimethyl-

Suppliers and Price of 5-amino-2,2-dimethyl-2H-pyran-3(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 5-amino-2,2-dimethyl-2H-pyran-3(6H)-one

Chemical Property:

PSA：52.32000
LogP:0.90720
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:141.078978594
Heavy Atom Count:10
Complexity:194

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(=O)C=C(CO1)N)C

Technology Process of 5-amino-2,2-dimethyl-2H-pyran-3(6H)-one

There total 5 articles about 5-amino-2,2-dimethyl-2H-pyran-3(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98272-63-0
2,2-dimethyl-2H-pyran-3,5-(4H,6H)-dione

: 372120-56-4
5-amino-2,2-dimethyl-6H-pyran-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: H₂SO₄ / 3 h / Heating

2: NH₃ / ethanol

With sulfuric acid; ammonia; In ethanol;
DOI:10.1021/jm060549u

Reference yield:

: 85428-68-8
(1,1-dimethylprop-2-ynyloxy)acetic acid methyl ester

: 372120-56-4
5-amino-2,2-dimethyl-6H-pyran-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂SO₄ / Hg(OAc)2 / methanol / 1 h / Heating

2: KO-t-Bu / 2-methyl-propan-2-ol; diethyl ether / 0.17 h / 0 °C

3: H₂SO₄ / 3 h / Heating

4: NH₃ / ethanol

With sulfuric acid; potassium tert-butylate; ammonia; mercury(II) diacetate; In methanol; diethyl ether; ethanol; tert-butyl alcohol;
DOI:10.1021/jm060549u

Reference yield:

: 115-19-5
2-methyl-but-3-yn-2-ol

: 372120-56-4
5-amino-2,2-dimethyl-6H-pyran-3-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: NaH / tetrahydrofuran / 0.58 h

1.2: tetrahydrofuran / 16.5 h / 0 - 20 °C

2.1: H₂SO₄ / Hg(OAc)2 / methanol / 1 h / Heating

3.1: KO-t-Bu / 2-methyl-propan-2-ol; diethyl ether / 0.17 h / 0 °C

4.1: H₂SO₄ / 3 h / Heating

5.1: NH₃ / ethanol

With sulfuric acid; potassium tert-butylate; ammonia; sodium hydride; mercury(II) diacetate; In tetrahydrofuran; methanol; diethyl ether; ethanol; tert-butyl alcohol;
DOI:10.1021/jm060549u