2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine

Base Information

Chemical Name:2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
CAS No.:459147-39-8
Molecular Formula:C21H20N2OS3
Molecular Weight:412.59
Hs Code.:
European Community (EC) Number:845-797-3
Pharos Ligand ID:86FFKXMTNAPD
ChEMBL ID:CHEMBL4061483
Mol file:459147-39-8.mol

Synonyms:SW033291

Suppliers and Price of 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SW033291
1mg
$ 305.00

TRC
SW033291
1mg
$ 45.00

Tocris
SW033291 ≥98%(HPLC)
50
$ 891.00

Tocris
SW033291 ≥98%(HPLC)
10
$ 212.00

Sigma-Aldrich
SW033291 ≥98% (HPLC)
5mg
$ 152.00

Sigma-Aldrich
SW033291 ≥98% (HPLC)
25mg
$ 610.00

DC Chemicals
SW033291 >98%
1 g
$ 1600.00

DC Chemicals
SW033291 >98%
250 mg
$ 800.00

Crysdot
SW033291 98+%
50mg
$ 356.00

Crysdot
SW033291 98+%
100mg
$ 520.00

Total 25 raw suppliers

Chemical Property of 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine

Chemical Property:

PSA：131.67000
LogP:7.62860
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:412.07377679
Heavy Atom Count:27
Complexity:514

Purity/Quality:

99%, ^*data from raw suppliers

SW033291 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCS(=O)C1=C(C2=C(S1)N=C(C=C2C3=CC=CC=C3)C4=CC=CS4)N
Uses SW033291 is an inhibitor which maintains the ability to promote tissue regeneration through inhibition of prostaglandin-degrading enzyme 15-PGDH.

Technology Process of 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine

There total 22 articles about 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2-(((butylsulfinyl)methyl)sulfanyl)-4-phenyl-6-(thiophen-2-yl)nicotinonitrile

: 459147-39-8
2-(butylsulfinyl)-4-phenyl-6-(thiophen-2-yl)thieno[2,3-b]pyridin-3-amine

Guidance literature:: With water; potassium hydroxide; In ethanol; N,N-dimethyl-formamide; at 35 ℃; for 0.666667h; Solvent;

Reference yield:

: 2-(((butylthio)methyl)sulfanyl)-4-phenyl-6-(thiophen-2-yl)nicotinonitrile

: 459147-39-8
2-(butylsulfinyl)-4-phenyl-6-(thiophen-2-yl)thieno[2,3-b]pyridin-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; dihydrogen peroxide / chloroform; water / 0.75 h / 32 °C

2: potassium hydroxide; water / N,N-dimethyl-formamide; ethanol / 0.67 h / 35 °C

With water; dihydrogen peroxide; acetic acid; potassium hydroxide; In ethanol; chloroform; water; N,N-dimethyl-formamide;

Reference yield:

: 3988-77-0,39078-33-6,69656-36-6
3-phenyl-1-thiophen-2-yl-propenone

: 459147-39-8
2-(butylsulfinyl)-4-phenyl-6-(thiophen-2-yl)thieno[2,3-b]pyridin-3-amine

Guidance literature:: Multi-step reaction with 4 steps

1: piperidine / ethanol / 3 h / Reflux

2: triethylamine / acetonitrile / 0.33 h / Reflux

3: acetic acid; dihydrogen peroxide / chloroform; water / 0.75 h / 32 °C

4: potassium hydroxide; water / N,N-dimethyl-formamide; ethanol / 0.67 h / 35 °C

With piperidine; water; dihydrogen peroxide; acetic acid; triethylamine; potassium hydroxide; In ethanol; chloroform; water; N,N-dimethyl-formamide; acetonitrile;