(4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine

Base Information

Chemical Name:(4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine
CAS No.:1228875-13-5
Molecular Formula:C6H12FNO
Molecular Weight:133.166
Hs Code.:2932999099
Mol file:1228875-13-5.mol

Synonyms:4-AMinoMethyl-4-fluoro-tetrahydro-2H-pyran;(4-fluorooxan-4-yl)methanamine;4-fluorotetrahydro-2H-Pyran-4-methan amine;(4-Fluorotetrahydro-2H-pyran-4-yl)

Suppliers and Price of (4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine
10mg
$ 45.00

SynQuest Laboratories
4-Aminomethyl-4-fluorotetrahydro-2H-pyran
250 mg
$ 344.00

Matrix Scientific
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine 95+%
250mg
$ 492.00

Crysdot
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine 95+%
1g
$ 515.00

Chemenu
(4-fluorooxan-4-yl)methanamine 95%
1g
$ 482.00

Alichem
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine
1g
$ 909.50

AK Scientific
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine
1g
$ 1524.00

AK Scientific
(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine
250mg
$ 714.00

Total 10 raw suppliers

Chemical Property of (4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine

Chemical Property:

Boiling Point:184.0±25.0 °C(Predicted)
PKA:10.01±0.29(Predicted)
PSA：35.25000
Density:1.06±0.1 g/cm3(Predicted)
LogP:1.16410
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

(4-Fluorotetrahydro-2H-pyran-4-yl)methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine

There total 7 articles about (4-fluorotetrahydro-2H-pyran-4-yl)MethanaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1454700-69-6
4-(azidomethyl)-4-fluorooxane

: 1228875-13-5
(4-fluorotetrahydro-2H-pyran-4-yl)methanamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield:

: 2-((4-fluorotetrahydro-2H-pyran-4-yl)methyl)isoindoline-1,3-dione

: 1228875-13-5
(4-fluorotetrahydro-2H-pyran-4-yl)methanamine

Guidance literature:: With hydrazine; In ethanol; at 70 ℃;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 1228875-13-5
(4-fluorotetrahydro-2H-pyran-4-yl)methanamine

Guidance literature:: Multi-step reaction with 6 steps

1: potassium tert-butylate / tert-butyl alcohol / 16 h / 20 °C

2: pyridine hydrofluoride / dichloromethane / 0 - 20 °C

3: sodium tetrahydroborate; water / isopropyl alcohol / 3 h / 0 - 20 °C

4: triethylamine / dichloromethane / 2 h / 0 - 20 °C

5: sodium hydrogencarbonate; sodium azide / N,N-dimethyl-formamide / 20 h / 120 °C

6: palladium 10% on activated carbon; hydrogen / ethyl acetate / 24 h / 20 °C / 760.05 Torr

With sodium tetrahydroborate; sodium azide; pyridine hydrofluoride; palladium 10% on activated carbon; potassium tert-butylate; water; hydrogen; sodium hydrogencarbonate; triethylamine; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol; tert-butyl alcohol;