2-CYANO-ALPHA-CHLOROBENZALDOXIME

Base Information

• Chemical Name: 2-CYANO-ALPHA-CHLOROBENZALDOXIME
• CAS No.: 943518-99-8
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.593
• Mol file: 943518-99-8.mol

Synonyms:2-CYANO-ALPHA-CHLOROBENZALDOXIME

Chemical Property of 2-CYANO-ALPHA-CHLOROBENZALDOXIME

Chemical Property:

• Boiling Point: 378.5±44.0 °C (760 mmHg)
• PSA: 56.38000
• Density: 1.28±0.1 g/cm3 (20 °C, 760 mmHg)
• LogP: 1.93288

Purity/Quality:

2-CYANO-ALPHA-CHLOROBENZALDOXIME 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CYANO-ALPHA-CHLOROBENZALDOXIME

There total 2 articles about 2-CYANO-ALPHA-CHLOROBENZALDOXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H6N2O (909772-06-1) → C8H5ClN2O (943518-99-8)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1021/acscombsci.7b00032

Reference yield:

o-formylbenzonitrile (7468-67-9) → C8H5ClN2O (943518-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / methanol; water / 3 h / 20 °C / Alkaline conditions

2: N-chloro-succinimide / N,N-dimethyl-formamide / 60 °C

With N-chloro-succinimide; hydroxylamine hydrochloride; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/acscombsci.7b00032

upstream raw materials:

C₈H₆N₂O

o-formylbenzonitrile