2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID

Base Information

Chemical Name:2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID
CAS No.:1028332-22-0
Molecular Formula:C6H5BCl2O3
Molecular Weight:206.821
Hs Code.:
Mol file:1028332-22-0.mol

Synonyms:2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID

Suppliers and Price of 2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(2,4-Dichloro-6-hydroxyphenyl)boronic acid 95%
250mg
$ 737.00

Matrix Scientific
(2,4-Dichloro-6-hydroxyphenyl)boronic acid 95%
1g
$ 1847.00

Chemenu
(2,4-Dichloro-6-hydroxyphenyl)boronicacid 97%
1g
$ 1051.00

American Custom Chemicals Corporation
2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID 95.00%
5G
$ 3075.45

Alichem
2,4-Dichloro-6-hydroxyphenylboronicacid
1g
$ 1072.62

Alichem
2,4-Dichloro-6-hydroxyphenylboronicacid
250mg
$ 425.00

Total 6 raw suppliers

Chemical Property of 2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID

Chemical Property:

Boiling Point:375.0±52.0 °C(Predicted)
PKA:8.11±0.45(Predicted)
PSA：60.69000
Density:1.63±0.1 g/cm3(Predicted)
LogP:0.37880

Purity/Quality:

97% ^*data from raw suppliers

(2,4-Dichloro-6-hydroxyphenyl)boronic acid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID

There total 8 articles about 2,4-DICHLORO-6-HYDROXYPHENYLBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1028332-21-9
2-(2,4-dichloro-6-(ethoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1028332-22-0
(2,4-dichloro-6-hydroxyphenyl)boronic acid

Guidance literature:: 2-(2,4-dichloro-6-(ethoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With boron tribromide; In dichloromethane; at 0 ℃; for 0.333333h;

With sodium hydroxide; In dichloromethane; water; pH=10;

With hydrogenchloride; In water; pH=3;

Reference yield:

: 1028332-21-9
2-(2,4-dichloro-6-(ethoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1028332-22-0
(2,4-dichloro-6-hydroxyphenyl)boronic acid

: 3,5-dichloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;

Reference yield:

: 591-35-5
3,5-dichlorophenol

: 1028332-22-0
(2,4-dichloro-6-hydroxyphenyl)boronic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / toluene; mineral oil / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

3.1: palladium diacetate; triethylamine; CyJohnPhos / 1,4-dioxane / 2 h / 80 °C / Inert atmosphere

4.1: boron tribromide / dichloromethane / 0.33 h / 0 °C / Inert atmosphere

4.2: Cooling

With palladium diacetate; boron tribromide; sodium hydride; potassium carbonate; triethylamine; CyJohnPhos; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/jm200128m