2-(p-Tolyl)ethylaMine HCl

Base Information

• Chemical Name: 2-(p-Tolyl)ethylaMine HCl
• CAS No.: 39260-86-1
• Molecular Formula: C9H14ClN
• Molecular Weight: 171.67
• Hs Code.: 2921499090
• Mol file: 39260-86-1.mol

Synonyms:2-(p-Tolyl)ethylaMine HCl;2-(p-Tolyl)EthanaMine hydrochloride;4-Methylphenethylamine hydrochloride

Chemical Property of 2-(p-Tolyl)ethylaMine HCl

Chemical Property:

• PSA: 26.02000
• LogP: 2.99850

Purity/Quality:

≥95% ^*data from raw suppliers

2-(P-Tolyl)ethylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(p-Tolyl)ethylaMine HCl

There total 8 articles about 2-(p-Tolyl)ethylaMine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C19H25N → p-Methylphenethylamine hydrochloride (39260-86-1)

Guidance literature:

With hydrogenchloride; In propan-1-ol; at 190 ℃; for 0.0833333h; Microwave irradiation; Green chemistry;

DOI:10.1080/00397911.2015.1100745

Reference yield: 81.0%

(4-methylphenyl)acetonitrile (2947-61-7) → p-Methylphenethylamine hydrochloride (39260-86-1)

Guidance literature:

(4-methylphenyl)acetonitrile; With borane-ammonia complex; C₁₇H₁₆BrMnN₂O₃S; In hexane; at 60 ℃; for 6h;

With hydrogenchloride; In diethyl ether; water;

DOI:10.1021/acscatal.0c05406

Reference yield: 73.0%

→ p-Methylphenethylamine hydrochloride (39260-86-1)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In ethanol; at 0 ℃; for 6h; Inert atmosphere;

upstream raw materials:

4-methyl-L-phenylalanine

2-(p-tolyl)ethylamine

(4-methylphenyl)acetonitrile

Downstream raw materials:

ethyl 1-(2-(4-methylphenyl)ethyl)-2,4,5-trioxoimidazolidine-3-acetate

1-(2-p-Tolyl-ethyl)-imidazolidine-2,4,5-trione

(2-p-Tolyl-ethyl)-urea

Refernces

• 1、 Ganguli, Kasturi,Mandal, Adarsha,Sarkar, Bidisha,Kundu, Sabuj. "Benzimidazole fragment containing Mn-complex catalyzed hydrosilylation of ketones and nitriles". . . Retrieved 2020/08/13.
• 2、 -. "METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY". Page/Page column 228. . Retrieved 2015/03/28.