(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol

Base Information

• Chemical Name: (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol
• CAS No.: 1434652-66-0
• Molecular Formula: C14H20O4
• Molecular Weight: 252.31
• Mol file: 1434652-66-0.mol

Synonyms:(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol;(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethanol

Chemical Property of (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol

Chemical Property:

• PSA: 47.92000
• LogP: 1.92420

Purity/Quality:

97% ^*data from raw suppliers

(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethanol 95+% ^*data from reagent suppliers

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Technology Process of (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol

There total 21 articles about (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)acetic acid → (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol (1434652-66-0)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; at 5 - 20 ℃; for 1h; Reagent/catalyst;

Reference yield: 95.0%

(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl butyrate → (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol (1434652-66-0)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; for 1h;

Reference yield: 83.0%

C16H22O5 → (R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol (1434652-66-0)

Guidance literature:

With methanol; sodium hydroxide; In water; at 0 - 20 ℃; for 2h;

upstream raw materials:

2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol

Tetrahydro-pyran-4-ol

ortho-anisaldehyde

2-(2-methoxyphenyl)oxirane

Downstream raw materials:

C₂₉H₃₃N₅O₇S

2-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidine-3(2H)-yl)-2-methylpropanoic acid

2-[1-[(2R)-2-hydroxy-2-(2-methoxyphenyl)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acid

1-[(2R)-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-3-(4H-1,2,4-triazol-3-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione

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