10-Keto DextroMethorphan

Base Information

Chemical Name:10-Keto DextroMethorphan
CAS No.:57969-05-8
Molecular Formula:C18H23NO2
Molecular Weight:285.386
Hs Code.:2933497050
Mol file:57969-05-8.mol

Synonyms:10-Keto DextroMethorphan;10-Keto;Dextromethorphan Impurity C

Suppliers and Price of 10-Keto DextroMethorphan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
(1R,9S,14S)-6-Methoxy-15-methyl-15-azatetracyclo[7.5.3.0~3,8~.0~9,14~]heptadeca-3,5,7-trien-2-one 90%
1g
$ 605.00

Total 8 raw suppliers

Chemical Property of 10-Keto DextroMethorphan

Chemical Property:

Melting Point:184-186°C
Boiling Point:446.2±45.0 °C(Predicted)
PKA:6.63±0.20(Predicted)
PSA：29.54000
Density:1.18±0.1 g/cm3(Predicted)
LogP:2.96150
Storage Temp.:Controlled Substance, -20?C Freezer

Purity/Quality:

99% ^*data from raw suppliers

(1R,9S,14S)-6-Methoxy-15-methyl-15-azatetracyclo[7.5.3.0~3,8~.0~9,14~]heptadeca-3,5,7-trien-2-one 90% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A product formed from the photochemical reaction of Dextromethorphan (D299455) after light or sunlight exposure.

Technology Process of 10-Keto DextroMethorphan

There total 10 articles about 10-Keto DextroMethorphan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 125-68-8,125-69-9,6031-86-3,111766-17-7
dextromethorphan hydrobromide

: 18050-88-9,57969-05-8
10-keto-3-methoxy-17-methyl-(9α,13α,14α)-morphinan

: 57912-50-2,111529-71-6,120442-81-1,133443-97-7
10β-hydroxy-3-methoxy-17-methyl-(9α,13α,14α)-morphinan

: 18609-21-7
C₁₈H₂₅NO*ClH

Guidance literature:: With oxygen; iron(III) chloride; In hydrogenchloride; for 22h; Irradiation; in borosilicate vessel;
DOI:10.1248/cpb.37.308

Reference yield: 59.0%

: 3-methoxymorphinan-10-one

: 77-78-1
dimethyl sulfate

: 57969-05-8
(9α,13α,14α)-3-methoxy-17-methylmorphinan-10-one

Guidance literature:: In toluene; for 2.5h; Solvent; Reflux;

Reference yield: 9.0%

: 125-71-3,1453167-99-1
dextromethorphan

: (9α,14α)-3-methoxy-17-methylmorphinan-10-ol

: 57969-05-8
(9α,13α,14α)-3-methoxy-17-methylmorphinan-10-one

Guidance literature:: With hydrogenchloride; iron(III) chloride hexahydrate; In water; acetonitrile; at 20 ℃; for 48h; chemoselective reaction;
DOI:10.1016/j.xphs.2018.10.059