Technology Process of 2,5-Diiodobenzonitrile
There total 2 articles about 2,5-Diiodobenzonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-cyano-4-iodobenzenediazonium tetrafluoroborate;
With
propylaminomethyl polystyrene resin; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1.08333h;
With
methyl iodide;
In
acetonitrile;
at 120 ℃;
for 18h;
DOI:10.1016/S0040-4020(02)01409-6
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 77 percent / BF3*Et2O; t-BuONO / tetrahydrofuran / 0.5 h / -20 - 5 °C
2.1: propylaminomethyl polystyrene resin; K2CO3 / tetrahydrofuran; dimethylformamide / 1.08 h / 0 - 20 °C
2.2: 33 mg / CH3I / acetonitrile / 18 h / 120 °C
With
tert.-butylnitrite; propylaminomethyl polystyrene resin; boron trifluoride diethyl etherate; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)01409-6
