4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Base Information

Chemical Name:4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CAS No.:300827-87-6
Molecular Formula:C16H25NO2HCl
Molecular Weight:299.841
Hs Code.:2922509090
Mol file:300827-87-6.mol

Synonyms:4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride;Desvenlafaxine hydrochloride

Suppliers and Price of 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Desvenlafaxine hydrochloride
50mg
$ 525.00

Sigma-Aldrich
Desvenlafaxine hydrochloride ≥98% (HPLC), powder
10mg
$ 195.00

Sigma-Aldrich
Desvenlafaxine hydrochloride ≥98% (HPLC), powder
50mg
$ 744.00

American Custom Chemicals Corporation
DESVENLAFAXINE HYDROCHLORIDE 95.00%
50MG
$ 1220.03

American Custom Chemicals Corporation
DESVENLAFAXINE HYDROCHLORIDE 95.00%
10MG
$ 713.71

Total 9 raw suppliers

Chemical Property of 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Chemical Property:

PSA：43.70000
LogP:3.53460
Storage Temp.:2-8°C
Solubility.:DMSO: >20mg/mL

Purity/Quality:

98%,99%, ^*data from raw suppliers

Desvenlafaxine hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Uses Desvenlafaxine Hydrochloride is a major active metabolite of venlafaxine (V120000), which is a slective serotonin noradrenaline reuptake inhibitor and used as an antidepressant. Desvenlafaxine hydrochloride has been used to evaluate if its occurrence in drinking water at environmental concentrations could induce neuronal gene expression.

Technology Process of 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

There total 3 articles about 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.5%

: 99300-78-4
venlafaxine hydrochloride

: 300827-87-6
O-desvenlafaxine hydrochloride

Guidance literature:: With methanesulfonic acid; L-methionine; Large scale;

Reference yield:

: 93413-62-8
O-desmethylvenlafaxine

: 300827-87-6
O-desvenlafaxine hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; water; Product distribution / selectivity; Reflux;

Reference yield:

: 93413-69-5
1-[2-dimethylamino-1-(4-methoxyphenyl)ethyl]cyclohexanol

: 300827-87-6
O-desvenlafaxine hydrochloride

Guidance literature:: 1-[2-dimethylamino-1-(4-methoxyphenyl)ethyl]cyclohexanol; With triisobutylaluminum; In toluene; at 20 ℃; for 20h; Reflux;

With water; In toluene; at 20 - 30 ℃;

With hydrogenchloride; In water; toluene; pH=5.0; Product distribution / selectivity;