(S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID

Base Information

Chemical Name:(S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID
CAS No.:164172-96-7
Molecular Formula:C₁₅H₁₅NO₂
Molecular Weight:241.29
Hs Code.:2922498590
Mol file:164172-96-7.mol

Synonyms:(S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID;L-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID

Suppliers and Price of (S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID 95.00%
0.25G
$ 275.00

Activate Scientific
(S)-2-Amino-3-biphenyl-3-yl-propionic acid 95+% ee
5 g
$ 1512.00

Activate Scientific
(S)-2-Amino-3-biphenyl-3-yl-propionic acid 95+% ee
1 g
$ 617.00

Activate Scientific
(S)-2-Amino-3-biphenyl-3-yl-propionic acid 95+% ee
250 mg
$ 296.00

Acrotein
(S)-2-Amino-3-biphenyl-3-yl-propionicacid 97%
1g
$ 440.00

Acrotein
(S)-2-Amino-3-biphenyl-3-yl-propionicacid 97%
0.25g
$ 192.50

ACHEMBLOCK
(S)-2-Amino-3-biphenyl-3-yl-propionicacid 95%
1G
$ 510.00

Total 6 raw suppliers

Chemical Property of (S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID

Chemical Property:

Boiling Point:423.9±33.0 °C(Predicted)
PKA:2.20±0.10(Predicted)
PSA：63.32000
Density:1.190±0.06 g/cm3(Predicted)
LogP:3.00830

Purity/Quality:

97% ^*data from raw suppliers

(S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID

There total 4 articles about (S)-2-AMINO-3-BIPHENYL-3-YL-PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 82311-69-1,99295-78-0
(S)-2-amino-3-(3-bromophenyl)propanoic acid

: 98-80-6
phenylboronic acid

: 164172-95-6,164172-96-7,887502-03-6
(S)-3-([1,1'-biphenyl]-3-yl)-2-aminopropanoic acid

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In water; isopropyl alcohol; at 80 ℃; for 24h; Sealed tube;
DOI:10.1002/cctc.201500190

Reference yield: 35.0%

: 1027167-32-3
1,1-dimethylethyl (2S)-trans-5-(<1,1'-biphenyl>-3-ylmethyl)-2-(1,1-dimethylethyl)-3-methyl-4-oxo-1-imidazolidinecarboxylate

: 164172-95-6,164172-96-7,887502-03-6
(S)-3-([1,1'-biphenyl]-3-yl)-2-aminopropanoic acid

Guidance literature:: With hydrogenchloride; for 2h; Heating;
DOI:10.1021/jm00011a015

Reference yield:

: 643-93-6
3-methylbiphenyl

: 164172-95-6,164172-96-7,887502-03-6
(S)-3-([1,1'-biphenyl]-3-yl)-2-aminopropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / NBS, (PhCO₂)2 / CCl₄ / 1.5 h / Heating; Irradiation

2: 1.) LDA / 1.) THF, hexane, from -78 to -20 deg C, 30 min, 2.) THF, hexane, -78 deg C, 3 h

3: 35 percent / 2N aq. HCl / 2 h / Heating

With hydrogenchloride; N-Bromosuccinimide; lithium diisopropyl amide; dibenzoyl peroxide; In tetrachloromethane;
DOI:10.1021/jm00011a015