Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate

Base Information

• Chemical Name: Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate
• CAS No.: 862094-14-2
• Molecular Formula: C13H16ClO3PS
• Molecular Weight: 318.756101
• Hs Code.: 2934999090
• Mol file: 862094-14-2.mol

Synonyms:Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate

Chemical Property of Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate

Chemical Property:

• PSA: 73.58000
• LogP: 5.32080
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Diethyl [(5-chloro-1-benzothiophen-3-yl)methyl]phosphonate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate

There total 1 articles about Diethyl [(5-chloro-1-benzothiophen-3-yl)Methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(bromomethyl)-5-chloro-1-benzothiophene (1198-51-2) + triethyl phosphite (122-52-1) → C13H16ClO3PS (862094-14-2)

Guidance literature:

for 0.0833333h; Heating;

DOI:10.1021/jm0700619

Reference yield:

C9H6FNO (343336-01-6) + C13H16ClO3PS (862094-14-2) → C22H22ClFNO4PS (936366-40-4)

Guidance literature:

C₁₃H₁₆ClO₃PS; With n-butyllithium; In hexane; toluene; at -78 ℃; for 0.75h;

C₉H₆FNO; In hexane; toluene; at -78 ℃; for 0.5h; Further stages.;

DOI:10.1021/jm0700619

Reference yield:

C9H5F2NO (936366-62-0) + C13H16ClO3PS (862094-14-2) → C22H21ClF2NO4PS (936366-41-5)

Guidance literature:

C₁₃H₁₆ClO₃PS; With n-butyllithium; In hexane; toluene; at -78 ℃; for 0.75h;

C₉H₅F₂NO; In hexane; toluene; at -78 ℃; for 0.5h; Further stages.;

DOI:10.1021/jm0700619

upstream raw materials:

3-(bromomethyl)-5-chloro-1-benzothiophene

triethyl phosphite

Downstream raw materials:

C₂₂H₂₂ClFNO₄PS

C₂₂H₂₁ClF₂NO₄PS

C₂₃H₂₅ClNO₅PS

{(5-chloro-benzo[b]thiophen-3-yl)-[2-(3,4-difluoro-phenyl)-vinylcarbamoyl]-methyl}-methyl-phosphonic acid