1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI)

Base Information

• Chemical Name: 1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI)
• CAS No.: 344747-26-8
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.181
• Mol file: 344747-26-8.mol

Synonyms:1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI)

Chemical Property of 1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI)

There total 3 articles about 1-Cyclopentene-1-carboxylic acid, 2-(hydroxymethyl)-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.9%

C11H14O6 → methyl 2-(hydroxymethyl)cyclopent-1-ene-1-carboxylate (344747-26-8)

Guidance literature:

With sodium tetrahydroborate; water; In tetrahydrofuran; at 10 - 20 ℃; Ice-cooling;

DOI:10.1002/hlca.200900003

Reference yield:

dimethylcyclopentene-1,2-dicarboxylate (13368-79-1) → methyl 2-(hydroxymethyl)cyclopent-1-ene-1-carboxylate (344747-26-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / methanol

With sodium hydroxide; In methanol;

DOI:10.1021/jo00179a039

Reference yield:

cyclopent-1-ene-1,2-dicarboxylic acid monomethyl ester (344751-62-8) → methyl 2-(hydroxymethyl)cyclopent-1-ene-1-carboxylate (344747-26-8)

Guidance literature:

DOI:10.1021/jo00179a039

upstream raw materials:

cyclopent-1-ene-1,2-dicarboxylic acid monomethyl ester

dimethylcyclopentene-1,2-dicarboxylate

Downstream raw materials:

2-Hydroxymethyl-cyclopent-1-en-1-carbonsaeure