2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl

Base Information

Chemical Name:2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl
CAS No.:870703-70-1
Molecular Formula:C18H21BrO2
Molecular Weight:349.268
Hs Code.:
European Community (EC) Number:624-663-6
DSSTox Substance ID:DTXSID20584751
Wikidata:Q82476459
Mol file:870703-70-1.mol

Synonyms:870703-70-1;2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl;2'-bromo-2,6-diisopropoxy-1,1'-biphenyl;2-(2-bromophenyl)-1,3-di(propan-2-yloxy)benzene;SCHEMBL367342;DTXSID20584751;AKOS025295855;CS-0457534;2-BROMO-2,6-DIISOPROPOXY-1,1-BIPHENYL;2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl, 95%;2'-Bromo-2,6-bis[(propan-2-yl)oxy]-1,1'-biphenyl

Suppliers and Price of 2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-Bromo-2′,6′-diisopropoxy-1,1′-biphenyl 95%
5g
$ 60.00

Sigma-Aldrich
2-Bromo-2′,6′-diisopropoxy-1,1′-biphenyl 95%
25g
$ 192.00

American Custom Chemicals Corporation
2-BROMO-2',6'-DIISOPROPOXY-1,1'-BIPHENYL 95.00%
10G
$ 1679.66

American Custom Chemicals Corporation
2-BROMO-2',6'-DIISOPROPOXY-1,1'-BIPHENYL 95.00%
5G
$ 1138.78

American Custom Chemicals Corporation
2-BROMO-2',6'-DIISOPROPOXY-1,1'-BIPHENYL 95.00%
1G
$ 721.59

AK Scientific
2-Bromo-2′,6′-diisopropoxy-1,1′-biphenyl
5g
$ 129.00

Total 6 raw suppliers

Chemical Property of 2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl

Chemical Property:

Refractive Index:n20/D 1.562
Boiling Point:140 °C/0.2 mmHg
Flash Point:110 °C
PSA：18.46000
Density:1.231 g/mL at 25 °C
LogP:5.69050
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:348.07249
Heavy Atom Count:21
Complexity:288

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-2′,6′-diisopropoxy-1,1′-biphenyl 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:N
Statements: 50/53
Safety Statements: 60-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC1=C(C(=CC=C1)OC(C)C)C2=CC=CC=C2Br

Technology Process of 2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl

There total 2 articles about 2-Bromo-2',6'-diisopropoxy-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 694-80-4
2-bromo-1-chlorobenzene

: 79128-08-8
1,3-diisopropoxybenzene

: 870703-70-1
2-(2-bromophenyl)-1,3-diisopropyloxybenzene

Guidance literature:: 1,3-diisopropoxybenzene; With n-butyllithium; In hexane; for 2.5h; Heating;

2-bromo-1-chlorobenzene; In hexane; for 1.83333h; Heating;
DOI:10.1021/ja0474493

Reference yield:

: 108-46-3
recorcinol

: 870703-70-1
2-(2-bromophenyl)-1,3-diisopropyloxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: 95 percent / K₂CO₃ / dimethylformamide / 24 h / 70 °C

2.1: n-BuLi / hexane / 2.5 h / Heating

2.2: hexane / 1.83 h / Heating

With n-butyllithium; potassium carbonate; In hexane; N,N-dimethyl-formamide;
DOI:10.1021/ja0474493

Reference yield: 81.0%

: (2R_P,4S_C,5R_C)-(+)-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazaphospholidine borane

: 870703-70-1
2-(2-bromophenyl)-1,3-diisopropyloxybenzene

: (SP)-(2′,6′-diisopropoxybiphenyl-2-yl)[(1R,2S)-N-ephedrino]-(phenyl)phosphine P-borane

Guidance literature:: 2-(2-bromophenyl)-1,3-diisopropyloxybenzene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 2h; Inert atmosphere;

(2R_P,4S_C,5R_C)-(+)-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazaphospholidine borane; In tetrahydrofuran; diethyl ether; hexane; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/jo400565b