5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile

Base Information

Chemical Name:5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile
CAS No.:1261600-44-5
Molecular Formula:C13H7F3N2
Molecular Weight:248.207
Hs Code.:
Mol file:1261600-44-5.mol

Synonyms:5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile;5-(4-(TrifluoroMethyl)phenyl)nicotinonitrile

Suppliers and Price of 5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(4-(Trifluoromethyl)phenyl)nicotinonitrile 95+%
1g
$ 668.00

Chemenu
5-(4-(trifluoromethyl)phenyl)nicotinonitrile 95%
1g
$ 632.00

American Custom Chemicals Corporation
5-(4-(TRIFLUOROMETHYL)PHENYL)NICOTINONITRILE 95.00%
5MG
$ 504.82

Alichem
5-(4-(Trifluoromethyl)phenyl)nicotinonitrile
1g
$ 1579.40

Alichem
5-(4-(Trifluoromethyl)phenyl)nicotinonitrile
250mg
$ 504.00

Total 5 raw suppliers

Chemical Property of 5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile

Chemical Property:

PSA：36.68000
LogP:3.63908
Storage Temp.:2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

5-(4-(Trifluoromethyl)phenyl)nicotinonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile

There total 1 articles about 5-(4-(trifluoromethyl)phenyl)pyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 35590-37-5
5-bromopyridine-3-carbonitrile

: 214360-65-3
4-trifluoromethylphenylboronic acid pinacol ester

: 1261600-44-5
5-[4-(trifluoromethyl)phenyl]pyridine-3-carbonitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 14h; Inert atmosphere; Sealed tube;

Reference yield: 74.0%

: 1261600-44-5
5-[4-(trifluoromethyl)phenyl]pyridine-3-carbonitrile

: 1346691-45-9
C-[5-(4-trifluoromethylphenyl)-pyridin-3-yl]methylamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 25 ℃; for 3h; under 2585.81 Torr;

Reference yield:

: 1261600-44-5
5-[4-(trifluoromethyl)phenyl]pyridine-3-carbonitrile

: 1590397-39-9
2-[(4-fluorobenzenesulfonyl)(isopropyl)-amino]-N-[5-(4-trifluoromethylphenyl)-pyridin-3-ylmethyl]-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 3 h / 25 °C / 2585.81 Torr

2: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 2 h / 25 °C

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; In ethanol; dichloromethane;