(E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene

Base Information

Chemical Name:(E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene
CAS No.:71441-45-7
Molecular Formula:C24H30
Molecular Weight:318.501
Hs Code.:
Nikkaji Number:J325.997H
Mol file:71441-45-7.mol

Synonyms:1,2,3,4-tetrahydro-1,1,4,4,-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene;arotinoid Ro 13-92972;methylarotinoid;Ro 13-9272;Ro-13-9272

Suppliers and Price of (E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYLAROTINOID 95.00%
5MG
$ 496.17

Total 4 raw suppliers

Chemical Property of (E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene

Chemical Property:

Vapor Pressure:7.53E-07mmHg at 25°C
Boiling Point:419.2°C at 760 mmHg
Flash Point:230.4°C
PSA：0.00000
Density:0.958g/cm³
LogP:6.90450
XLogP3:8.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:318.234750957
Heavy Atom Count:24
Complexity:458

Purity/Quality:

99% ^*data from raw suppliers

METHYLAROTINOID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C=C(C)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
Isomeric SMILES:CC1=CC=C(C=C1)/C=C(\C)/C2=CC3=C(C=C2)C(CCC3(C)C)(C)C

Technology Process of (E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene

There total 5 articles about (E)-1,2,3,4-Tetrahydro-1,1,4,4-tetramethyl-6-(1-(4-methylphenyl)-1-propen-2-yl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.8%

: 104-87-0
4-methyl-benzaldehyde

: 69251-24-7
[1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-ethyl]-triphenylphosphonium bromide

: 71441-45-7
p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-toluene

Guidance literature:: With tetrahydrofuran; at 65 ℃; for 12h;

Reference yield:

: 17610-21-8
1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethanone

: 71441-45-7
p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-toluene

Guidance literature:: Multi-step reaction with 4 steps

1: sodium borohydride / methanol / 1.5 h / 0 °C

2: phosphorus tribromide / pyridine / diethyl ether; hexane / 2.5 h / 0 - 5 °C

3: diethyl ether; xylene / 48 h / 100 °C

4: 45.8 percent / butylene oxide / 12 h / 65 °C

With tetrahydrofuran; sodium tetrahydroborate; phosphorus tribromide; pyridine; In methanol; diethyl ether; hexane; xylene;

Reference yield:

: 69251-25-8
5,6,7,8-tetrahydro-α,5,5,8,8-pentamethyl-2-naphthalene methanol

: 71441-45-7
p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-toluene

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus tribromide / pyridine / diethyl ether; hexane / 2.5 h / 0 - 5 °C

2: diethyl ether; xylene / 48 h / 100 °C

3: 45.8 percent / butylene oxide / 12 h / 65 °C

With tetrahydrofuran; phosphorus tribromide; pyridine; In diethyl ether; hexane; xylene;