(R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE

Base Information

• Chemical Name: (R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE
• CAS No.: 1001646-85-0
• Molecular Formula: C23H34N2O6
• Molecular Weight: 434.533
• Hs Code.: 2933399090
• Mol file: 1001646-85-0.mol

Synonyms:(R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE;(R)-4-(3-BENZYLOXYCARBONYLAMINO-3-METHOXYCARBONYL-PROPYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Chemical Property of (R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE

Chemical Property:

• PSA: 94.17000
• LogP: 4.21050

Purity/Quality:

NLT 98% ^*data from raw suppliers

(R)-1-Boc-4-(3-Cbz-Amino-3-methoxycarbonyl-propyl)piperidine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE

There total 2 articles about (R)-1-BOC-4-(3-CBZ-AMINO-3-METHOXYCARBONYL-PROPYL)PIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(3-benzyloxycarbonylamino-3-methoxycarbonyl-allyl)-piperidine-1-carboxylic acid tert-butyl ester (871675-56-8) → C23H34N2O6 (1001646-85-0)

Guidance literature:

With hydrogen; (+)-1,2-bis-((2S,5S)-2,5-diethylphospholano)benzene(cyclooctadiene) rhodium(I) trifluoromethanesulfonate; In methanol; at 20 ℃; for 24h; under 3102.97 Torr;

Reference yield:

C23H32N2O6 (890849-78-2) → C23H34N2O6 (1001646-85-0)

Guidance literature:

With hydrogen; (R,R)-ethyl-DuPHOS-Rh(COD) triflate; In methanol; at 20 ℃; for 24h; under 3102.97 Torr;

upstream raw materials:

4-(3-benzyloxycarbonylamino-3-methoxycarbonyl-allyl)-piperidine-1-carboxylic acid tert-butyl ester

C₂₃H₃₂N₂O₆

Refernces

• 1、 -. "COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS". Page/Page column 24-25. . Retrieved 2008/12/08.
• 2、 -. "Compounds and Compositions as Channel Activating Protease Inhibitors". Page/Page column 24-25. . Retrieved 2008/06/13.