3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)

Base Information

Chemical Name:3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)
CAS No.:377082-44-5
Molecular Formula:C₉H₁₅NO₃
Molecular Weight:185.223
Hs Code.:
Mol file:377082-44-5.mol

Synonyms:3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)

Suppliers and Price of 3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Ethyl6-methoxy-2,3,4,5-tetrahydropyridine-5-carboxylate
100mg
$ 421.00

Total 1 raw suppliers

Chemical Property of 3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)

Chemical Property:

PSA：47.89000
LogP:0.44000

Purity/Quality:: Ethyl6-methoxy-2,3,4,5-tetrahydropyridine-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI)

There total 2 articles about 3-Pyridinecarboxylicacid,3,4,5,6-tetrahydro-2-methoxy-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 420-37-1
trimethoxonium tetrafluoroborate

: 3731-16-6
3-carboethoxy-2-pyridone

: 377082-44-5
2-methoxy-3,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester

Guidance literature:: In chloroform; at 20 ℃; for 6h;

Reference yield:

: 377082-44-5
2-methoxy-3,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester

Guidance literature:

Reference yield:

: 377082-44-5
2-methoxy-3,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester

: 4-{2-[8-(2-carboxy-2-phenylmethanesulfonylamino-ethylcarbamoyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-yl]-vinyl}-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.2: methanol / Heating

2.1: aq. LiOH / tetrahydrofuran

3.1: HBTU; HOBt / acetonitrile

4.1: aq. LiOH / tetrahydrofuran

With lithium hydroxide; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In tetrahydrofuran; acetonitrile;
DOI:10.1016/S0960-894X(01)00529-7