4-Biphenylboronic acid MIDA ester

Base Information

• Chemical Name: 4-Biphenylboronic acid MIDA ester
• CAS No.: 1262967-24-7
• Molecular Formula: C17H16BNO4
• Molecular Weight: 309.12424
• Mol file: 1262967-24-7.mol

Synonyms:4-Biphenylboronic acid MIDA ester;2-([1,1′-Biphenyl]-4-yl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione

Chemical Property of 4-Biphenylboronic acid MIDA ester

Chemical Property:

• Melting Point: 182-192°C
• PSA: 55.84000
• LogP: 1.01850
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

4-Biphenylboronic acid MIDA ester 95% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Protected boronic acid with methylimindodiacetic acid (MIDA) that does not react under standard Suzuki-Miyuara coupling conditions, allowing for selective and iterative cross-coupling sequences. The MIDA boronate also provides prolonged shelf life and stability to typically unstable boronic acid derivatives.Please see our Technology Spotlight

Technology Process of 4-Biphenylboronic acid MIDA ester

There total 1 articles about 4-Biphenylboronic acid MIDA ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-methyliminodiacetic acid (4408-64-4) + 4-biphenylboronic acid (5122-94-1) → 4-biphenylboronic acid MIDA ester (1262967-24-7)

Guidance literature:

In N,N-dimethyl-formamide; at 100 ℃; for 16h;

DOI:10.1021/acs.orglett.5b03030

upstream raw materials:

N-methyliminodiacetic acid

4-biphenylboronic acid

Refernces