1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL

Base Information

• Chemical Name: 1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL
• CAS No.: 86099-06-1
• Molecular Formula: C₁₆H₂₀N₂O₇
• Molecular Weight: 352.344
• Mol file: 86099-06-1.mol

Synonyms:1,11-BISMALEIMIDIO TETRAETHYLENEGLYCOL;1,8-BISMALEIMIDIO TETRAETHYLENEGLYCOL;1,1'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-1H-pyrrole-2,5-dione;1,11-Bis(MaleiMido)-3,6,9-trioxaundecane;N,N'-3,6,9-Trioxadecane- 1,11-bisMaleiMide;1,11-Bis-MaleiMidodriethyleneglycol(BM[PEO]3)

Chemical Property of 1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL

Chemical Property:

• Melting Point: 71-72°C
• Boiling Point: 526.9±45.0 °C(Predicted)
• PKA: -2.04±0.20(Predicted)
• PSA: 102.45000
• Density: 1.335±0.06 g/cm3(Predicted)
• LogP: -1.23800

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,11-Bis(maleimido)tetraethyleneglycol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL

There total 2 articles about 1,11-BIS-MALEIMIDOTETRAETHYLENEGLYCOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C24H28N2O9 (1449655-93-9) → 1,11-bis(maleimido)triethylene glycol (86099-06-1)

Guidance literature:

In 1,1,2,2-tetrachloroethane; at 120 ℃; for 12h;

DOI:10.1016/j.tetlet.2013.07.002

Reference yield:

1-bromo-2-{2-[2-(2-bromoethoxy)ethoxy]-ethoxy}ethane (31255-26-2) → 1,11-bis(maleimido)triethylene glycol (86099-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 50 °C / Inert atmosphere

2: 1,1,2,2-tetrachloroethane / 12 h / 120 °C

With potassium carbonate; In N,N-dimethyl-formamide; 1,1,2,2-tetrachloroethane;

DOI:10.1016/j.tetlet.2013.07.002

upstream raw materials:

C₂₄H₂₈N₂O₉

1-bromo-2-{2-[2-(2-bromoethoxy)ethoxy]-ethoxy}ethane

Refernces