Chemical Property of REVEROMYCIN D
Chemical Property:
- Boiling Point:855.3±65.0 °C(Predicted)
- PKA:4.36±0.17(Predicted)
- PSA：176.89000
- Density:1.20±0.1 g/cm3(Predicted)
- LogP:6.52140
- Purity/Quality:
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>95% by HPLC *data from raw suppliers
ReveromycinD *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μg/ml at pH 3 and 7.4, respectively). Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively).
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Uses
Reveromycin D is the isopentyl analogue and a minor component of the reveromycin complex, isolated from a Streptomyces sp.. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C. Reveromycin D is a minor component of the reveromycin complex.
