1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL

Base Information

• Chemical Name: 1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL
• CAS No.: 914347-67-4
• Molecular Formula: C₉H₁₂BrN₃O
• Molecular Weight: 258.118
• Mol file: 914347-67-4.mol

Synonyms:1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL;1-(5-BroMopyriMidin-2-yl)piperidin-3-ol;1-(5-Bromopyrimidin-2-yl)

Chemical Property of 1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL

Chemical Property:

• Vapor Pressure: 9.42E-08mmHg at 25°C
• Boiling Point: 418.5°C at 760 mmHg
• Flash Point: 206.9°C
• PSA: 49.25000
• Density: 1.6g/cm³
• LogP: 1.26520
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1-(5-Bromopyrimidin-2-yl)-3-piperidinol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL

There total 1 articles about 1-(5-BROMOPYRIMIDIN-2-YL)-3-PIPERIDINOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

5-Bromo-2-chloropyrimidine (32779-36-5) + (R)-piperidin-3-ol hydrochloride (198976-43-1) → (3R)-1-(5-bromopyrimidin-2-yl)piperidin-3-ol (914347-67-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 80 ℃; for 1h; Microwave irradiation;

upstream raw materials:

5-Bromo-2-chloropyrimidine

(R)-piperidin-3-ol hydrochloride

Refernces