5-Bromo-3-nitropyridine-2...

Base Information

• Chemical Name: 5-Bromo-3-nitropyridine-2...
• CAS No.: 1086838-46-1
• Molecular Formula: C₆H₃BrN₂O₃
• Molecular Weight: 231.005
• Hs Code.: 2933399090
• Mol file: 1086838-46-1.mol

Synonyms:5-Bromo-3-nitropyridine-2...;5-BroMo-3-nitropyridine-2-carbaldehyde;5-BroMo-3-nitropyridin-2-carbaldehyde;5-Bromo-3-nitropicolinaldehyde;5-bromo-3-nitropyridine-2-carboxaldehyde

Chemical Property of 5-Bromo-3-nitropyridine-2...

Chemical Property:

• Boiling Point: 316.6±42.0 °C(Predicted)
• PKA: -3.56±0.10(Predicted)
• PSA: 75.78000
• Density: 1.888±0.06 g/cm3(Predicted)
• LogP: 2.08800

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Bromo-3-nitropyridine-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Bromo-3-nitropyridine-2...

There total 2 articles about 5-Bromo-3-nitropyridine-2... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine (1227628-14-9) → 5-bromo-3-nitropicolinaldehyde (1086838-46-1)

Guidance literature:

With sodium periodate; water; In tetrahydrofuran; at 25 ℃; for 3h; Product distribution / selectivity;

Reference yield: 62.0%

→ 5-bromo-3-nitropicolinaldehyde (1086838-46-1)

Guidance literature:

Reference yield: 24.13%

5-bromo-3-nitropicolinaldehyde (1086838-46-1) → 3-amino-5-bromopicolinaldehyde (1289168-19-9)

Guidance literature:

With iron; acetic acid; In ethanol; at 0 - 25 ℃; for 1h;

upstream raw materials:

2-(5-bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine

Downstream raw materials:

3-amino-5-bromopicolinaldehyde

Refernces

• 1、 -. "ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF". Page/Page column 112. . Retrieved 2009/01/20.