2-Bromo-1-(difluoromethyl)-4-fluorobenzene

Base Information

Chemical Name:2-Bromo-1-(difluoromethyl)-4-fluorobenzene
CAS No.:845866-81-1
Molecular Formula:C7H4BrF3
Molecular Weight:225.008
Hs Code.:2903999090
European Community (EC) Number:685-087-9
DSSTox Substance ID:DTXSID20375606
Wikidata:Q82164198
Mol file:845866-81-1.mol

Synonyms:2-bromo-1-(difluoromethyl)-4-fluorobenzene;845866-81-1;2-Bromo-1-difluoromethyl-4-fluorobenzene;2-Bromo-4-fluorobenzodifluoride;MFCD06657961;2-bromo-1-(difluoromethyl)-4-fluoro-benzene;SCHEMBL1337142;DTXSID20375606;BBL101039;STL554833;AKOS005256031;FS-4225;1-Bromo-2-(difluoromethyl)-5-fluorobenzene;CS-0149503;FT-0678870;2-Bromo-1-(Diflluoromethyl)-4-Fluorobenzene;EN300-185463;2-Bromo-1-(difluoromethyl)-4-fluorobenzene, 97%;A840864;2-Bromo-1-difluoromethyl-4-fluorobenzene stabilized over potassium carbonate

Suppliers and Price of 2-Bromo-1-(difluoromethyl)-4-fluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-1-(difluoromethyl)-4-fluorobenzene
100mg
$ 60.00

Sigma-Aldrich
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 97%
1g
$ 27.50

Matrix Scientific
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 98%
5g
$ 99.00

Matrix Scientific
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 98%
1g
$ 25.00

Apolloscientific
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 98%
5g
$ 121.00

Apolloscientific
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 98%
25g
$ 440.00

American Custom Chemicals Corporation
2-BROMO-1-DIFLUOROMETHYL-4-FLUOROBENZENE 95.00%
5G
$ 888.20

American Custom Chemicals Corporation
2-BROMO-1-DIFLUOROMETHYL-4-FLUOROBENZENE 95.00%
1G
$ 612.15

Ambeed
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 97%
5g
$ 170.00

Ambeed
2-Bromo-1-(difluoromethyl)-4-fluorobenzene 97%
1g
$ 58.00

Total 17 raw suppliers

Chemical Property of 2-Bromo-1-(difluoromethyl)-4-fluorobenzene

Chemical Property:

Vapor Pressure:0.62mmHg at 25°C
Refractive Index:n20/D1.495
Boiling Point:194.4°C at 760 mmHg
Flash Point:80°C
PSA：0.00000
Density:1.711 g/mL at 25 °C
LogP:3.52580
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:223.94485
Heavy Atom Count:11
Complexity:129

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-(difluoromethyl)-4-fluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 23-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)Br)C(F)F

Technology Process of 2-Bromo-1-(difluoromethyl)-4-fluorobenzene

There total 1 articles about 2-Bromo-1-(difluoromethyl)-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 59142-68-6
2-bromo-4-fluorobenzaldehyde

: 845866-81-1
2-bromo-1-(difluoromethyl)-4-fluorobenzene

Guidance literature:: With diethylamino-sulfur trifluoride; In ethanol; dichloromethane; at 0 ℃; Reflux;

Reference yield: 70.0%

: 845866-81-1
2-bromo-1-(difluoromethyl)-4-fluorobenzene

: 1402601-93-7
methyl 3-(4-ethynyl-2-fluorophenyl)propanoate

: 1402602-07-6
methyl 3-(4-((2-(difluoromethyl)-5-fluorophenyl)ethynyl)-2-fluorophenyl)propanoate

Guidance literature:: With copper(l) iodide; sodium tetrachloropalladate(II); N,N,N,N,-tetramethylethylenediamine; di‐tert‐butyl‐(1‐phenylindol‐2‐yl)phosphane; In water; at 80 ℃; Inert atmosphere;
DOI:10.1021/ml4000673

Reference yield: 60.0%

: 845866-81-1
2-bromo-1-(difluoromethyl)-4-fluorobenzene

: 78191-00-1
N-Methoxy-N-methylacetamide

: 1-(2-(difluoromethyl)-5-fluorophenyl)ethanone

Guidance literature:: 2-bromo-1-(difluoromethyl)-4-fluorobenzene; With n-butyllithium; In diethyl ether; at -78 ℃; for 1h; Inert atmosphere;

N-Methoxy-N-methylacetamide; In diethyl ether; for 2h;