(3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]

Base Information

• Chemical Name: (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]
• CAS No.: 1581276-63-2
• Molecular Formula: C35H56O7
• Molecular Weight: 588.81494
• Mol file: 1581276-63-2.mol

Synonyms:(3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate];O-Tigloylgymnemagenin, 21-;21-O-Tigloylgymnemagenin

Chemical Property of (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]

Chemical Property:

• PSA: 127.45000
• LogP: 4.54320

Purity/Quality:

≥98% ^*data from raw suppliers

O-Tigloylgymnemagenin, 21- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]

There total 4 articles about (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-escin → escygenin (1581276-63-2)

Guidance literature:

β-escin; With sulfuric acid; In methanol; at 24 - 45 ℃; for 3.33333h; Reflux;

With potassium hydroxide; In methanol; water; at 45 - 50 ℃; pH=7;

Reference yield:

21-O-tigloylprotoaescigenin 3-O-[β-D-glucopyranosyl-(1->2)][β-D-glucopyranosyl-(1->4)]-β-D-glucuronopyranosyl acid → 21-O-tigloylprotoaescigenin (7047-43-0,1581276-63-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 80 ℃; for 2h;

DOI:10.1248/cpb.47.1515

Reference yield:

→ 21-Angelikyl-protoaescigenin (7047-43-0,35931-54-5,85279-15-8,85279-16-9,1581276-63-2)

Guidance literature:

21-Angelikyl-22-acetyl-protoaescigenin, methanol. NaOH;

DOI:10.1016/S0040-4039(01)99139-7

Downstream raw materials:

barringtogenol C

protoaescigenin