3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE

Base Information

• Chemical Name: 3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE
• CAS No.: 192699-67-5
• Molecular Formula: C₁₃H₈N₂O₂
• Molecular Weight: 224.219
• Hs Code.: 2926909090
• Mol file: 192699-67-5.mol

Synonyms:3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE;AKOS BAR-1983;3-(3-Nitrophenyl)benzonitrile

Chemical Property of 3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE

Chemical Property:

• PSA: 69.61000
• LogP: 3.65668

Purity/Quality:

97% ^*data from raw suppliers

3''-Nitro-[1,1''-biphenyl]-3-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE

There total 3 articles about 3'-NITRO[1,1'-BIPHENYL]-3-CARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

m-nitrobromobenzene (585-79-5) + (3‐cyanophenyl)boronic acid (150255-96-2) → 3'-nitrobiphenyl-3-carbonitrile (192699-67-5)

Guidance literature:

With β-D-mannose; palladium diacetate; potassium carbonate; In water; N,N-dimethyl-formamide; at 130 ℃; Microwave irradiation; Green chemistry;

DOI:10.1039/c5ra04129e

Reference yield:

m-nitrobenzene boronic acid (13331-27-6) + (3‐cyanophenyl)boronic acid (150255-96-2) → 3,3'-dicyanobiphenyl (36852-02-5) + 3,3'-dinitro-1,1'-biphenyl (958-96-3) + 3'-nitrobiphenyl-3-carbonitrile (192699-67-5)

Guidance literature:

With copper(l) chloride; In methanol; at 25 ℃;

DOI:10.1002/ejoc.201001729

Reference yield:

3-chloro-benzonitrile (766-84-7) + 3-nitrobenzoic acid (121-92-6) → 3'-nitrobiphenyl-3-carbonitrile (192699-67-5)

Guidance literature:

3-nitrobenzoic acid; With potassium tert-butylate; In ethanol; at 20 ℃; Inert atmosphere;

3-chloro-benzonitrile; With copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; tetrakis(acetonitrile)palladium bistriflate; XPhos; In 1-methyl-pyrrolidin-2-one; quinoline; at 190 ℃; for 16h; Inert atmosphere;

DOI:10.1002/anie.201505843

upstream raw materials:

m-nitrobenzene boronic acid

(3‐cyanophenyl)boronic acid

m-nitrobromobenzene

3-chloro-benzonitrile