3-Keto-7α,12α-dihydroxy-5α-cholanic Acid

Base Information

Chemical Name:3-Keto-7α,12α-dihydroxy-5α-cholanic Acid
CAS No.:16265-24-0
Molecular Formula:C24H38O5
Molecular Weight:406.56
Hs Code.:

Synonyms:3-Keto-7α,12α-dihydroxy-5α-cholanic Acid;(5α,7α,12α)-7,12-Dihydroxy-3-oxo-cholan-24-oic Acid;5α,7α,12α-Dihydroxy-3-oxocholanic Acid

Suppliers and Price of 3-Keto-7α,12α-dihydroxy-5α-cholanic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Keto-7α,12α-dihydroxy-5α-cholanicAcid
25mg
$ 680.00

Medical Isotopes, Inc.
3-Keto-7α,12α-dihydroxy-5α-cholanicAcid
5 mg
$ 620.00

Total 2 raw suppliers

Chemical Property of 3-Keto-7α,12α-dihydroxy-5α-cholanic Acid

Chemical Property:

Melting Point:218-221°C
PSA：94.83000
LogP:3.65690
Storage Temp.:-20°C Freezer
Solubility.:DMF, DMSO, Methanol (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

3-Keto-7α,12α-dihydroxy-5α-cholanicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 3-Keto-7α,12α-dihydroxy-5α-cholanic Acid (cas# 16265-24-0) is a compound useful in organic synthesis.

Technology Process of 3-Keto-7α,12α-dihydroxy-5α-cholanic Acid

There total 6 articles about 3-Keto-7α,12α-dihydroxy-5α-cholanic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 125626-77-9
7α,12α-dihydroxy-3-oxochola-1,4-dien-24-oic acid

: 16265-24-0
7α,12α-dihydroxy-5α-cholan-3-one-24-oic acid

Guidance literature:: With ammonia; lithium; In tetrahydrofuran; for 0.333333h; Ambient temperature;
DOI:10.1248/cpb.41.763

Reference yield:

: 33744-75-1
methyl 3α,7α,12α-triformyloxy-5β-cholanoate

: 16265-24-0
7α,12α-dihydroxy-5α-cholan-3-one-24-oic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / ammonia / methanol / 0.5 h / Ambient temperature

2: 70 percent / iodoxybenzene, benzeneseleninic anhydride / toluene / 3 h / Heating

3: 87 percent / 2 M LiOH / methanol / 1.5 h / Ambient temperature

4: lithium, liq. ammonia / tetrahydrofuran / 0.33 h / Ambient temperature

With lithium hydroxide; benzeneseleninic anhydride; ammonia; lithium; iodosylbenzene; In tetrahydrofuran; methanol; toluene;
DOI:10.1248/cpb.41.763

Reference yield:

: 1448-36-8
methyl cholate

: 16265-24-0
7α,12α-dihydroxy-5α-cholan-3-one-24-oic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / 60percent perchloric acid / 1.5 h / 50 °C

2: 100 percent / ammonia / methanol / 0.5 h / Ambient temperature

3: 70 percent / iodoxybenzene, benzeneseleninic anhydride / toluene / 3 h / Heating

4: 87 percent / 2 M LiOH / methanol / 1.5 h / Ambient temperature

5: lithium, liq. ammonia / tetrahydrofuran / 0.33 h / Ambient temperature

With lithium hydroxide; perchloric acid; benzeneseleninic anhydride; ammonia; lithium; iodosylbenzene; In tetrahydrofuran; methanol; toluene;
DOI:10.1248/cpb.41.763