3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester

Base Information

Chemical Name:3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester
CAS No.:329932-55-0
Molecular Formula:C23H17N3O8
Molecular Weight:463.403
Hs Code.:
DSSTox Substance ID:DTXSID80365023
Nikkaji Number:J2.810.122H
Wikidata:Q27210371
ChEMBL ID:CHEMBL1542356
Mol file:329932-55-0.mol

Synonyms:FM19G11

Suppliers and Price of 3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
FM19G11 ≥98%(HPLC)
25
$ 463.00

Tocris
FM19G11 ≥98%(HPLC)
5
$ 119.00

Sigma-Aldrich
FM19G11 ≥98% (HPLC)
25mg
$ 569.00

Sigma-Aldrich
FM19G11 ≥98% (HPLC)
5mg
$ 141.00

Biosynth Carbosynth
FM 19G11 NEW
50 mg
$ 437.50

Biosynth Carbosynth
FM 19G11 NEW
10 mg
$ 125.00

Axon Medchem
FM19G11 99%
2 x 5 mg
$ 154.00

American Custom Chemicals Corporation
FM-19G11 95.00%
25MG
$ 1029.63

American Custom Chemicals Corporation
FM-19G11 95.00%
5MG
$ 697.51

AK Scientific
3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoicacid[2-(4-methylphenyl)-2-oxoethyl]ester
10mg
$ 218.00

Total 8 raw suppliers

Chemical Property of 3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester

Chemical Property:

PSA：167.60000
LogP:5.53380
Storage Temp.:2-8°C
Solubility.:DMSO: ≥40mg/mL
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:463.10156451
Heavy Atom Count:34
Complexity:784

Purity/Quality:

98%,99%, ^*data from raw suppliers

FM19G11 ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)COC(=O)C2=CC(=CC=C2)NC(=O)C3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-]
Uses FM19G11 has been used as ahypoxia-inducible factor-1α (HIF- 1α):to study the effects ofFM19G11-loaded gold nanoparticles (NPs) on self-renewal and proliferation of ependymal stem progenitor cells (epSPCs) of mice to study its effects on the O6-methylguanine DNA-methyltransferase (MGMT) expression in glioblastoma (GBM) cells to study its effects on microphthalmia-associated transcription factor (MITF) expression in melanoma cell line

Technology Process of 3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester

There total 4 articles about 3-[[(2,4-Dinitrophenyl)-oxomethyl]amino]benzoic acid [2-(4-methylphenyl)-2-oxoethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 906131-02-0
3-((2,4-dinitro)benzamido)benzoic acid

: 619-41-0
4-(bromoacetyl)toluene

: 329932-55-0
FMG₁₉G₁₁

Guidance literature:: 3-((2,4-dinitro)benzamido)benzoic acid; With caesium carbonate; In ethanol; water; pH=6.5;

4-(bromoacetyl)toluene; In N,N-dimethyl-formamide; for 3h;

Reference yield:

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 329932-55-0
FMG₁₉G₁₁

Guidance literature:: Multi-step reaction with 4 steps

1.1: thionyl chloride / 16 h / 0 °C

2.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 3 h

3.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 16 h

4.1: caesium carbonate / ethanol; water / pH 6.5

4.2: 3 h

With thionyl chloride; lithium hydroxide monohydrate; water; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; water;

Reference yield:

: 4518-10-9
Methyl 3-aminobenzoate

: 329932-55-0
FMG₁₉G₁₁

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 3 h

2.1: water; lithium hydroxide monohydrate / tetrahydrofuran / 16 h

3.1: caesium carbonate / ethanol; water / pH 6.5

3.2: 3 h

With lithium hydroxide monohydrate; water; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; water;