FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-

Base Information

Chemical Name:FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-
CAS No.:4257-54-9
Molecular Formula:C₁₆H₉FO₅
Molecular Weight:300.243
Hs Code.:
Mol file:4257-54-9.mol

Synonyms:FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-

Suppliers and Price of FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-FLAVONE 95.00%
5MG
$ 503.80

Total 0 raw suppliers

Chemical Property of FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-

Chemical Property:

Vapor Pressure:2.44E-09mmHg at 25°C
Melting Point:116 °C
Boiling Point:462.2°C at 760 mmHg
PKA:8.20±0.20(Predicted)
Flash Point:233.3°C
PSA：68.90000
Density:1.583g/cm³
LogP:3.03340

Purity/Quality:: 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-FLAVONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)-

There total 3 articles about FLAVONE, 6-FLUORO-3-HYDROXY-3',4'-(METHYLENEDIOXY)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 3-(Benzo[1,3]dioxol-5-yl)-1-(5-fluoro-2-hydroxyphenyl)-2-propen-1-one

: 4257-54-9
2-(benzo[d][1,3]dioxol-5-yl)-6-fluoro-3-hydroxy-4H-chromen-4-one

Guidance literature:: With dihydrogen peroxide; sodium hydroxide; In ethanol; at 20 ℃; Cooling with ice;
DOI:10.1021/acsmedchemlett.8b00565

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

: 4257-54-9
2-(benzo[d][1,3]dioxol-5-yl)-6-fluoro-3-hydroxy-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 20 °C

2: sodium hydroxide; dihydrogen peroxide / ethanol / 20 °C / Cooling with ice

With dihydrogen peroxide; sodium hydroxide; In ethanol; 1: |Claisen-Schmidt Condensation;
DOI:10.1021/acsmedchemlett.8b00565