2,6-Bis(bromomethyl)-4-nitropyridine

Base Information

Chemical Name:2,6-Bis(bromomethyl)-4-nitropyridine
CAS No.:358621-46-2
Molecular Formula:C7H6Br2N2O2
Molecular Weight:309.94274
Hs Code.:
DSSTox Substance ID:DTXSID20579248
Nikkaji Number:J1.960.961H
Wikidata:Q82469727
Mol file:358621-46-2.mol

Synonyms:2,6-Bis(bromomethyl)-4-nitropyridine;358621-46-2;DTXSID20579248

Suppliers and Price of 2,6-Bis(bromomethyl)-4-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,6-Bis(bromomethyl)-4-nitropyridine

Chemical Property:

PSA：58.71000
LogP:3.30280
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:309.87755
Heavy Atom Count:13
Complexity:174

Purity/Quality:: 96% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=C(N=C1CBr)CBr)[N+](=O)[O-]

Technology Process of 2,6-Bis(bromomethyl)-4-nitropyridine

There total 5 articles about 2,6-Bis(bromomethyl)-4-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 2,6-bis(tribromomethyl)-4-nitropyridine

: 358621-46-2
2,6-bis(bromomethyl)-4-nitropyridine

Guidance literature:: With Diethyl phosphonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;
DOI:10.1021/jo0301393

Reference yield: 34.0%

: 4913-57-9
4-nitro-2,6-dimethylpyridine

: 358621-46-2
2,6-bis(bromomethyl)-4-nitropyridine

Guidance literature:: 4-nitro-2,6-dimethylpyridine; With N-Bromosuccinimide; In benzene; at 70 ℃; for 72h; Irradiation; Sealed tube;

With N-ethyl-N,N-diisopropylamine; phosphonic acid diethyl ester; In tetrahydrofuran; at 0 - 20 ℃; for 0.25h;
DOI:10.1021/acs.joc.0c00188

Reference yield:

: 1073-23-0
2,6-lutidine N-oxide

: 358621-46-2
2,6-bis(bromomethyl)-4-nitropyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: nitric acid; sulfuric acid / 24 h / 85 °C

2.1: phosphorus trichloride / chloroform / 4 h / 0 - 62 °C

3.1: N-Bromosuccinimide / benzene / 72 h / 80 °C / Irradiation; Sealed tube

3.2: 0 - 20 °C

With N-Bromosuccinimide; sulfuric acid; nitric acid; phosphorus trichloride; In chloroform; benzene;
DOI:10.1039/c9dt04714j