2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine

Base Information

Chemical Name:2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine
CAS No.:372183-70-5
Molecular Formula:C13H12ClFN2
Molecular Weight:250.7
Hs Code.:2933599090
DSSTox Substance ID:DTXSID20696520
Wikidata:Q82626139
Mol file:372183-70-5.mol

Synonyms:372183-70-5;2-CHLORO-4-[2-(4-FLUOROPHENYL)ETHYL]-6-METHYLPYRIMIDINE;2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine;1706462-30-7;2-Chloro-4-[2-(4-fluorophenyl)-ethyl]-6-methylpyrimidine;DTXSID20696520;AKOS027379803;CS-0359151;2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine, AldrichCPR

Suppliers and Price of 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-4-[2-(4-fluorophenyl)-ethyl]-6-methylpyrimidine
5g
$ 1498.00

Matrix Scientific
2-Chloro-4-[2-(4-fluorophenyl)-ethyl]-6-methylpyrimidine
10g
$ 2600.00

Matrix Scientific
2-Chloro-4-[2-(4-fluorophenyl)-ethyl]-6-methylpyrimidine
1g
$ 553.00

Crysdot
2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine 97%
1g
$ 520.00

Crysdot
2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine 97%
10g
$ 2451.00

Crysdot
2-Chloro-4-(4-fluorophenethyl)-6-methylpyrimidine 97%
5g
$ 1412.00

Biosynth Carbosynth
2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
1 g
$ 637.10

Biosynth Carbosynth
2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
500 mg
$ 400.00

Biosynth Carbosynth
2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
100 mg
$ 164.00

Biosynth Carbosynth
2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
50 mg
$ 102.50

Total 6 raw suppliers

Chemical Property of 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine

Chemical Property:

Vapor Pressure:2.81E-08mmHg at 25°C
Boiling Point:449.6°C at 760 mmHg
PKA:3.48±0.10(Predicted)
Flash Point:225.7°C
PSA：25.78000
Density:1.296g/cm³
LogP:3.36270
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:250.0673042
Heavy Atom Count:17
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-4-[2-(4-fluorophenyl)-ethyl]-6-methylpyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)Cl)CCC2=CC=C(C=C2)F

Technology Process of 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine

There total 2 articles about 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 3934-20-1
2,6-Dichloropyrimidine

: 64-04-0
phenethylamine

: 372183-70-5
4-chloro-N-phenethylpyrimidin-2-amine

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 5h;
DOI:10.1021/acs.jmedchem.0c01712

Reference yield:

: 64-04-0
phenethylamine

: 97229-10-2
4-chloro-2-(methylsulfinyl)pyrimidine

: 372183-70-5
4-chloro-N-phenethylpyrimidin-2-amine

Guidance literature:: In tetrahydrofuran; at 25 ℃; for 2h;

Reference yield: 67.0%

: 109-01-3
1-methyl-piperazine

: 372183-70-5
4-chloro-N-phenethylpyrimidin-2-amine

: 1201173-75-2
4-(4-methylpiperazin-1-yl)-N-phenethylpyrimidin-2-amine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tert-Amyl alcohol; at 130 ℃; for 1h; Microwave irradiation;
DOI:10.1021/acs.jmedchem.0c01712