Nifurmerone

Base Information

Chemical Name:Nifurmerone
CAS No.:5579-95-3
Molecular Formula:C6H4 Cl N O4
Molecular Weight:189.555
Hs Code.:
NSC Number:84429
UNII:F57Y390K2N
DSSTox Substance ID:DTXSID90204358
Nikkaji Number:J8.004G
Wikidata:Q27277663
NCI Thesaurus Code:C72592
Metabolomics Workbench ID:155830
ChEMBL ID:CHEMBL2106787
Mol file:5579-95-3.mol

Synonyms:NIFURMERONE;5579-95-3;Metofurone;NF-71;Nifurmerona;Nifurmeronum;Ethanone, 2-chloro-1-(5-nitro-2-furanyl)-;NF 71;2-Chloro-1-(5-nitrofuran-2-yl)ethan-1-one;Chloromethyl 5-nitro-2-furyl ketone;NSC-84429;Nifurmerone [USAN:INN];Ketone, chloromethyl 5-nitro-2-furyl;UNII-F57Y390K2N;F57Y390K2N;(Chlormethyl)(5-nitro-2-furyl)keton;2-Chloro-1-(5-nitro-2-furyl)ethanone;2-chloro-1-(5-nitrofuran-2-yl)ethanone;C6H4ClNO4;NIFURMERONE [INN];Nifurmerone (USAN/INN);NIFURMERONE [USAN];2-chloroacetyl-5-nitrofuran;SCHEMBL398798;C6-H4-Cl-N-O4;5-NITRO-2-FURYL KETONE;CHEMBL2106787;DTXSID90204358;NSC84429;CCG-40502;NSC 84429;AKOS006273133;AKOS040753267;D05163;EN300-1268482;Q27277663;Z1198155433

Suppliers and Price of Nifurmerone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Nifurmerone
500mg
$ 618.00

Total 6 raw suppliers

Chemical Property of Nifurmerone

Chemical Property:

Vapor Pressure:0.00486mmHg at 25°C
Melting Point:92.5-94 °C
Boiling Point:276.2°Cat760mmHg
Flash Point:120.9°C
PSA：76.03000
Density:1.492g/cm³
LogP:2.13250
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:188.9828853
Heavy Atom Count:12
Complexity:202

Purity/Quality:

95% ^*data from raw suppliers

Nifurmerone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(OC(=C1)[N+](=O)[O-])C(=O)CCl
Uses Antifungal.

Technology Process of Nifurmerone

There total 4 articles about Nifurmerone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 645-12-5
5-nitro-2-furoic acid

: 5579-95-3
2-(α-chloroacetyl)-5-nitrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / thionyl chloride / benzene / 2 h / Heating

2: 2) HCl gas / 1) ether, overnight

With hydrogenchloride; thionyl chloride; In benzene;

Reference yield:

: 98130-85-9
2-diazo-1-(5-nitro-[2]furyl)-ethanone

: 5579-95-3
2-(α-chloroacetyl)-5-nitrofuran

Guidance literature:: With hydrogenchloride; diethyl ether;

Reference yield:

: 25084-14-4
5-nitrofuran-2-carboxylic chloride

: 5579-95-3
2-(α-chloroacetyl)-5-nitrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether

2: hydrogen chloride; diethyl ether

With hydrogenchloride; diethyl ether;