(E)-4-tetradecyloxycinnamic acid

Base Information

• Chemical Name: (E)-4-tetradecyloxycinnamic acid
• CAS No.: 318531-43-0
• Molecular Formula: C₂₃H₃₆O₃
• Molecular Weight: 360.537
• Mol file: 318531-43-0.mol

Synonyms:(E)-4-tetradecyloxycinnamic acid

Chemical Property of (E)-4-tetradecyloxycinnamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-tetradecyloxycinnamic acid

There total 7 articles about (E)-4-tetradecyloxycinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

malonic acid (141-82-2) + 4-tetradecyloxybenzaldehyde (59117-17-8) → (E)-4-tetradecyloxycinnamic acid (318531-43-0)

Guidance literature:

With piperidine; In pyridine; at 60 - 120 ℃; for 5h;

DOI:10.1080/15421406.2010.526563

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → (E)-4-tetradecyloxycinnamic acid (318531-43-0)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; piperidine / Reflux

2: potassium hydroxide / methanol / Reflux

With piperidine; pyridine; potassium hydroxide; In methanol;

DOI:10.1080/15421406.2012.698234

Reference yield:

p-Coumaric Acid (7400-08-0,50940-26-6) → (E)-4-tetradecyloxycinnamic acid (318531-43-0)

Guidance literature:

With potassium hydroxide; In methanol; Reflux;

DOI:10.1080/15421406.2012.698234 DOI:10.1080/15421406.2014.884392

upstream raw materials:

malonic acid

4-tetradecyloxybenzaldehyde

4-hydroxy-benzaldehyde

p-Coumaric Acid

Downstream raw materials:

4-n-tetradecyloxycinnamoyl chloride