7alpha-Hydroxyandrost-4-ene-3,17-dione

Base Information

Chemical Name:7alpha-Hydroxyandrost-4-ene-3,17-dione
CAS No.:62-84-0
Molecular Formula:C₁₉H₂₆O₃
Molecular Weight:302.414
Hs Code.:
DSSTox Substance ID:DTXSID10977537
Nikkaji Number:J337.164F
Wikidata:Q27103317
Metabolomics Workbench ID:35352
ChEMBL ID:CHEMBL4582005
Mol file:62-84-0.mol

Synonyms:7 alpha-hydroxy-4-androstene-3,17-dione;7-hydroxy-4-androstene-3,17-dione

Suppliers and Price of 7alpha-Hydroxyandrost-4-ene-3,17-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 7alpha-Hydroxyandrost-4-ene-3,17-dione

Chemical Property:

Vapor Pressure:4.15E-11mmHg at 25°C
Boiling Point:477.1°C at 760 mmHg
Flash Point:256.5°C
PSA：0.00000
Density:1.19g/cm³
LogP:0.00000
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:302.18819469
Heavy Atom Count:22
Complexity:577

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)C(CC4=CC(=O)CCC34C)O
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)[C@@H](CC4=CC(=O)CC[C@]34C)O
Uses 7α-Hydroxyandrostenedione is a metabolite of of Androstenedione (A637550). 7α-Hydroxyandrostenedione inhibits the transformation of pregnenolone (P712200) to progesterone (P755900) by the Δ5-3β-hydroxy steroid dehydrogenase coupled with the Δ5-Δ4 isomerase in rat testicular microsomal fractions.

Technology Process of 7alpha-Hydroxyandrost-4-ene-3,17-dione

There total 12 articles about 7alpha-Hydroxyandrost-4-ene-3,17-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.7%

: 63-05-8
Androstenedione

: 2243-05-2
5α-androst-3,6,17-trione

: 564-33-0
11α-hydroxyandrost-4-ene-3,17-dione

: 62-84-0,31427-20-0
7α-hydroxyandrost-4-ene-3,17-dione

: 63-00-3
6β-hydroxy-4-androstene-3,17-dione

Guidance literature:: With water; In N,N-dimethyl-formamide; at 28 ℃; Rhizopus nigricans;
DOI:10.1007/BF00765613

Reference yield: 45.0%

: 63-05-8
Androstenedione

: 564-63-6
14-hydroxy-4-androstene-3,17-dione

: 62-84-0,31427-20-0
7α-hydroxyandrost-4-ene-3,17-dione

: 63-00-3
6β-hydroxy-4-androstene-3,17-dione

: 31427-20-0
7β-hydroxy-4-androstene-3,17-dione

Guidance literature:: With Absidia griseolla var. igachii; In ethanol; at 24 ℃; for 96h; Microbiological reaction;
DOI:10.1016/j.molcatb.2016.01.007