<1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Base Information

Chemical Name:<1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle
CAS No.:146036-90-0
Molecular Formula:C₂₀H₃₃N₂O₆P
Molecular Weight:428.466
Hs Code.:

Synonyms:<1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Suppliers and Price of <1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

There total 2 articles about <1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 15761-38-3
L-N-Boc-Ala

: 77526-73-9
(1-Amino-2-phenylethyl)phosphonsaeure-diethylester

: 146036-90-0
<1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane; for 0.75h; Ambient temperature;
DOI:10.1016/S0040-4020(01)92278-1

Reference yield:

: 146036-80-8
(1-Isocyanato-2-phenyl)ethylphosphonate de diethyle

: 146036-90-0
<1-(tert-Butyloxycarbonyl-L-alanyl-amino)-2-phenyl>ethylphosphonate de diethyle

Guidance literature:: Multi-step reaction with 2 steps

1: 1) 12 N HCl, 2) K₂CO₃ / 1) Et₂O, reflux, 30 min, 2) H₂O

2: 88 percent / BOP, NEt₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

With hydrogenchloride; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane;
DOI:10.1016/S0040-4020(01)92278-1