Fananserin

Base Information

Chemical Name:Fananserin
CAS No.:127625-29-0
Molecular Formula:C23H24 F N3 O2 S
Molecular Weight:425.527
Hs Code.:
UNII:38QJ762ET6
DSSTox Substance ID:DTXSID8046743
Nikkaji Number:J380.289B
Wikipedia:Fananserin
Wikidata:Q5433633
NCI Thesaurus Code:C80768
Pharos Ligand ID:TR73ZKZJDHZZ
Metabolomics Workbench ID:144352
ChEMBL ID:CHEMBL83894
Mol file:127625-29-0.mol

Synonyms:2-(3-(4-(4-fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxide;fananserin;fananserine;RP 62203;RP-62203

Suppliers and Price of Fananserin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fananserin
10mg
$ 403.00

TRC
Fananserin
2.5mg
$ 165.00

Tocris
Fananserin ≥99%(HPLC)
10
$ 155.00

Tocris
Fananserin ≥99%(HPLC)
50
$ 558.00

ChemScene
Fananserin 99.83%
5mg
$ 188.00

ChemScene
Fananserin 99.83%
10mg
$ 320.00

ApexBio Technology
Fananserin
10mg
$ 245.00

ApexBio Technology
Fananserin
50mg
$ 975.00

American Custom Chemicals Corporation
FANANSERIN 95.00%
50MG
$ 1073.29

Total 11 raw suppliers

Chemical Property of Fananserin

Chemical Property:

Vapor Pressure:2.48E-16mmHg at 25°C
Boiling Point:641.1°Cat760mmHg
Flash Point:341.5°C
PSA：52.24000
Density:1.331g/cm³
LogP:4.84860
Storage Temp.:Store at RT
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:425.15732635
Heavy Atom Count:30
Complexity:683

Purity/Quality:

97% ^*data from raw suppliers

Fananserin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCCN2C3=CC=CC4=C3C(=CC=C4)S2(=O)=O)C5=CC=C(C=C5)F
Uses Antipsychotic. Fananserin is an antagonist of 5-HT2A.

Technology Process of Fananserin

There total 6 articles about Fananserin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 127625-83-6
2-(3-chloropropyl)-2H-naphth<1,8-cd>isothiazole 1,1-dioxide

: 2252-63-3
1-(4-Fluorophenyl)piperazine

: 127625-29-0
fananserin

Guidance literature:: With triethylamine; In toluene; 1.) reflux, 8 h, 2.) RT, 15 h;
DOI:10.1021/jm00112a025

Reference yield: 65.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 2-(3-Piperazin-1-yl-propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide

: 127625-29-0
fananserin

Guidance literature:: With sodium t-butanolate; Pd catalyst; In toluene; at 110 ℃; for 2h;

Reference yield:

: 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-5-trimethylstannanyl-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide

: 127625-29-0
fananserin

: 5-Chloro-2-{3-[4-(4-fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide

: 4-[125I]-RP 62203

Guidance literature:: With sodium hydroxide; sodium (12?I)iodide; chloroamine-T; acetic acid; In methanol; water; for 0.0333333h; Ambient temperature;
DOI:10.1002/(SICI)1099-1344(199802)41:2<143::AID-JLCR63>3.0.CO;2-P