1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan

Base Information

• Chemical Name: 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan
• CAS No.: 434321-76-3
• Molecular Formula: C₁₈H₁₆F₇OP
• Molecular Weight: 412.287
• Mol file: 434321-76-3.mol

Synonyms:1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan

Chemical Property of 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan

There total 1 articles about 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

Trifluoro-methanesulfonate1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1-phosphonia-indan; → 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ5-phospha-indan (434321-76-3)

Guidance literature:

With lithium tetrafluoroborate; In diethyl ether; at 20 ℃;

DOI:10.1246/cl.2002.268

Reference yield: 100.0%

trimethylsilyl trifluoromethanesulfonate (27607-77-8) + 1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ5-phospha-indan (434321-76-3) → Trifluoro-methanesulfonate1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1-phosphonia-indan;

Guidance literature:

In diethyl ether; at 20 ℃;

DOI:10.1246/cl.2002.268

Reference yield:

1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ5-phospha-indan (434321-76-3) → 1,1,1,3-tetrahydro-1-isopropylidene-1-phenyl-3,3-bis(trifluoromethyl)-2,1-benzoxaphosphole (461679-37-8)

Guidance literature:

1-fluoro-1-isopropyl-1-phenyl-3,3-bis-trifluoromethyl-2-oxa-1λ⁵-phospha-indan; With trimethylsilyl trifluoromethanesulfonate; In diethyl ether; at 20 ℃;

With mesityllithium; In tetrahydrofuran; at -72 ℃;

DOI:10.1080/10426500213458

Downstream raw materials:

1,1,1,3-tetrahydro-1-isopropylidene-1-phenyl-3,3-bis(trifluoromethyl)-2,1-benzoxaphosphole

3',3'-dimethyl-1-phenyl-3,3-bis(trifluoromethyl)spiro[3H-2,1-benzoxaphosphole-1,2'λ⁵-[1,2]selenaphosphirane]