N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine

Base Information

• Chemical Name: N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine
• CAS No.: 192320-25-5
• Molecular Formula: C₂₂H₂₈N₂O₆S
• Molecular Weight: 448.54
• Mol file: 192320-25-5.mol

Synonyms:N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine

Chemical Property of N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine

There total 3 articles about N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine (192320-25-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / pyridine

2: 4-dimethylaminopyridine / acetonitrile / -10 deg C, 1 h; 4 h RT

With dmap; In pyridine; acetonitrile;

DOI:10.3891/acta.chem.scand.52-0627

Reference yield:

N-tosylethylenediamine (14316-16-6) → N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine (192320-25-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / pyridine

2: 4-dimethylaminopyridine / acetonitrile / -10 deg C, 1 h; 4 h RT

With dmap; In pyridine; acetonitrile;

DOI:10.3891/acta.chem.scand.52-0627

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + [2-(Toluene-4-sulfonylamino)-ethyl]-carbamic acid benzyl ester (208525-21-7) → N-tert-butoxycarbonyl-N-tosyl-N'-benzyloxycarbonyl-1,2-ethylenediamine (192320-25-5)

Guidance literature:

With dmap; In acetonitrile; Yield given; -10 deg C, 1 h; 4 h RT;

DOI:10.3891/acta.chem.scand.52-0627

upstream raw materials:

di-tert-butyl dicarbonate

[2-(Toluene-4-sulfonylamino)-ethyl]-carbamic acid benzyl ester

benzyl chloroformate

N-tosylethylenediamine

Downstream raw materials:

N¹-benzyloxycarbonyl-N²-t-butoxycarbonyl-1,2-ethanediamine