6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde

Base Information

Chemical Name:6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde
CAS No.:105378-65-2
Molecular Formula:C21H19 N O
Molecular Weight:301.38
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00147101
Wikidata:Q83012177
Mol file:105378-65-2.mol

Synonyms:6,7-diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde;DADHP-5-acetaldehyde

Suppliers and Price of 6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde

Chemical Property:

Vapor Pressure:2.37E-09mmHg at 25°C
Boiling Point:479.4°C at 760 mmHg
PKA:-2.88±0.20(Predicted)
Flash Point:243.7°C
PSA：22.00000
Density:1.13g/cm³
LogP:4.50970
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:301.146664230
Heavy Atom Count:23
Complexity:397

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C(=C(N2C1)CC=O)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde

There total 3 articles about 6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 105378-64-1
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-vic-dihydroxyethan

: 105378-65-2
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-acetaldehyd

Guidance literature:: With hydrogenchloride; In acetone; for 1h; Ambient temperature;
DOI:10.1002/ardp.19863190605

Reference yield:

: 73009-96-8
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-oxalsaeurechlorid

: 105378-65-2
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-acetaldehyd

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / pyridine / 1 h / 40 - 50 °C

2: 87 percent / LiAlH₄ / tetrahydrofuran / 1 h / 40 °C

3: 60 percent / conc. aq. HCl / acetone / 1 h / Ambient temperature

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; acetone;
DOI:10.1002/ardp.19863190605

Reference yield:

: 105378-63-0
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-oxalsaeurebenzylester

: 105378-65-2
(6,7-Diphenyl-2,3-dihydro-1H-pyrrolizin-5-yl)-acetaldehyd

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / LiAlH₄ / tetrahydrofuran / 1 h / 40 °C

2: 60 percent / conc. aq. HCl / acetone / 1 h / Ambient temperature

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; acetone;
DOI:10.1002/ardp.19863190605