3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide

Base Information

• Chemical Name: 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide
• CAS No.: 201336-48-3
• Molecular Formula: C₁₉H₂₁N₃O₄S
• Molecular Weight: 387.459
• Mol file: 201336-48-3.mol

Synonyms:3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide

Chemical Property of 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide

There total 1 articles about 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

aminoglutethimide (125-84-8) + 3-amino-benzenesulfonyl fluoride (368-50-3) → 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide (201336-48-3)

Guidance literature:

With triethylamine; In acetonitrile; at 60 ℃; for 6h;

DOI:10.1016/S0223-5234(97)82776-6

Reference yield:

2,4,6-trimethylpyrylium chlorate(VII) (940-93-2) + 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide (201336-48-3) → 1-{3-[4-(3-Ethyl-2,6-dioxo-piperidin-3-yl)-phenylsulfamoyl]-phenyl}-2,4,6-trimethyl-pyridinium; perchlorate

Guidance literature:

With acetic acid; triethylamine; Yield given. Multistep reaction; 1.) 2 h, 2.) reflux, 3 h;

DOI:10.1016/S0223-5234(97)82776-6

Reference yield:

Tosyl isocyanate (4083-64-1) + 3-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide (201336-48-3) → 3-ethyl-3-{3-[4-(tosylsulfonylureido)phenylsulfamoyl]phenyl}-2,6-piperidinedione

Guidance literature:

In acetonitrile; for 1h; Yield given; Ambient temperature;

DOI:10.1016/S0223-5234(97)82776-6

upstream raw materials:

aminoglutethimide

3-amino-benzenesulfonyl fluoride