1-(4-methoxyphenyl)-1,3-butadiyne

Base Information

• Chemical Name: 1-(4-methoxyphenyl)-1,3-butadiyne
• CAS No.: 7642-31-1
• Molecular Formula: C₁₁H₈O
• Molecular Weight: 156.184
• Mol file: 7642-31-1.mol

Synonyms:1-(4-methoxyphenyl)-1,3-butadiyne

Chemical Property of 1-(4-methoxyphenyl)-1,3-butadiyne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methoxyphenyl)-1,3-butadiyne

There total 15 articles about 1-(4-methoxyphenyl)-1,3-butadiyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-methoxy-4-[4-(trimethylsilyl)-1,3-butadiyn-1-yl]benzene (130248-54-3) → 1-(4-methoxyphenyl)-1,3-butadiyne (7642-31-1)

Guidance literature:

With potassium carbonate; In methanol; at 25 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.1c00519

Reference yield: 84.0%

5-Hydroxy-5-methyl-1-(4-methoxylphenyl)hexa-1,3-diyne (117635-52-6) → 1-(4-methoxyphenyl)-1,3-butadiyne (7642-31-1)

Guidance literature:

With sodium hydroxide; In toluene; at 135 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1002/ejoc.200800618

Reference yield:

ethyl 5-(4-methoxyphenyl)-3-oxo-2-triphenylphosphoranylidenepent-4-ynoate (131292-07-4) → 1-(4-methoxyphenyl)-1,3-butadiyne (7642-31-1) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

at 750 ℃; for 1h; under 0.001 - 0.1 Torr;

DOI:10.1039/P19940002461

upstream raw materials:

ethyl 5-(4-methoxyphenyl)-3-oxo-2-triphenylphosphoranylidenepent-4-ynoate

1-(4-methoxyphenyl)butan-1,3-dione

Triethyl-[4-(4-methoxy-phenyl)-buta-1,3-diynyl]-silane

1-methoxy-4-[4-(trimethylsilyl)-1,3-butadiyn-1-yl]benzene

Downstream raw materials:

p-Methoxy-phenyl-hexatriin

Triethyl-[6-(4-methoxy-phenyl)-hexa-1,3,5-triynyl]-silane

Bis-p-anisyl-octatetrain

2-[4-(4-methoxyphenyl)buta-1,3-diynyl]pyrimidine