Technology Process of (E)-N-[(2R)-2-formyl-5-imino-1-(4-methoxyphenyl)-3-oxopentan-2-yl]-5-hydroxy-N-(2-hydroxy-4-methylpentanoyl)-6-(3-phenyloxiran-2-yl)hept-2-enamide
There total 288 articles about (E)-N-[(2R)-2-formyl-5-imino-1-(4-methoxyphenyl)-3-oxopentan-2-yl]-5-hydroxy-N-(2-hydroxy-4-methylpentanoyl)-6-(3-phenyloxiran-2-yl)hept-2-enamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3,3-dimethyldioxirane;
In
dichloromethane; acetone;
at -30 - 23 ℃;
for 12h;
DOI:10.1002/ejoc.200300814
- Guidance literature:
-
C34H44N2O9;
With
pyridinium p-toluenesulfonate; trimethyl orthoformate;
In
dichloromethane;
at 20 ℃;
for 1h;
With
Acetyl bromide;
In
dichloromethane;
at 20 ℃;
for 2h;
With
potassium hydrogencarbonate;
In
methanol; 1,2-dimethoxyethane; ethanol;
at 40 ℃;
for 6h;
stereoselective reaction;
DOI:10.1016/j.tetlet.2011.09.134