Technology Process of (S)-2-(2-iodobenzyl)-2-vinylindoline
There total 5 articles about (S)-2-(2-iodobenzyl)-2-vinylindoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; (Ra)-3,3’-di(anthracen-9-yl)-[1,1’-binaphthalene]-2,2’-diol; caesium carbonate;
In
1,4-dioxane;
at 20 ℃;
for 10h;
enantioselective reaction;
DOI:10.1021/ja306631z
- Guidance literature:
-
Multi-step reaction with 3 steps
2: trifluoroacetic acid; sodium carbonate
3: copper(l) iodide; caesium carbonate; (Ra)-3,3’-di(anthracen-9-yl)-[1,1’-binaphthalene]-2,2’-diol / 1,4-dioxane / 10 h / 20 °C
With
copper(l) iodide; (Ra)-3,3’-di(anthracen-9-yl)-[1,1’-binaphthalene]-2,2’-diol; sodium carbonate; caesium carbonate; trifluoroacetic acid;
In
1,4-dioxane;
1: |Swern Oxidation / 3: |Ullmann-Fetvadjian Synthesis;
DOI:10.1021/ja306631z
- Guidance literature:
-
Multi-step reaction with 5 steps
1: water; hydrogenchloride / ethanol / 20 °C
2: methanol; sodium tetrahydroborate / tetrahydrofuran
4: trifluoroacetic acid; sodium carbonate
5: copper(l) iodide; caesium carbonate; (Ra)-3,3’-di(anthracen-9-yl)-[1,1’-binaphthalene]-2,2’-diol / 1,4-dioxane / 10 h / 20 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; copper(l) iodide; (Ra)-3,3’-di(anthracen-9-yl)-[1,1’-binaphthalene]-2,2’-diol; water; sodium carbonate; caesium carbonate; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; ethanol;
3: |Swern Oxidation / 5: |Ullmann-Fetvadjian Synthesis;
DOI:10.1021/ja306631z
