N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

Base Information

Chemical Name:N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide
CAS No.:122183-17-9
Molecular Formula:C₃₁H₂₇N₅O₅
Molecular Weight:549.586
Hs Code.:

Synonyms:N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

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Technology Process of N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

There total 1 articles about N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 24115-90-0
2-nitro-3-benzyloxybenzoyl chloride

: 111861-12-2
2-(4-hydroxyphenyl)-5⁽⁶⁾-(1-piperazinyl)benzimidazole

: 122183-17-9
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

Guidance literature:: With triethylamine; In chloroform; N,N-dimethyl-formamide; for 1h;

Reference yield:

: 122183-17-9
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

: (2-Amino-3-hydroxy-phenyl)-{4-[2-(4-hydroxy-phenyl)-1H-benzoimidazol-5-yl]-piperazin-1-yl}-methanone

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;

Reference yield:

: 122183-17-9
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxybenzamide

: 122183-16-8
2-amino-1,9-di<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinylcarbonyl>-3H-3-oxophenoxyazine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / methanol / 760 Torr / Ambient temperature

2: p-quinone / methanol / 96 h / Ambient temperature

With hydrogen; p-benzoquinone; palladium on activated charcoal; In methanol;