Technology Process of C52H76N4O11
There total 5 articles about C52H76N4O11 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3,9-Bis(tert-butoxycarbonylmethyl)-6-carboxymethyl-3,6,9-triazaundecanedioic acid-di-tert-butyl ester;
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.166667h;
3,4-di(benzyloxy)phenethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
DOI:10.1002/chem.201101413
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 24.58 h / 0 - 20 °C
2.1: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 0 °C
3.1: acetonitrile / 24 h / pH 8 / aq. phosphate buffer
4.1: 5%-palladium/activated carbon; hydrogen / methanol / 24 h / 20 °C
5.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C
5.2: 20 °C
With
N-Bromosuccinimide; 5%-palladium/activated carbon; hydrogen; potassium hydrogencarbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; triphenylphosphine;
In
methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1002/chem.201101413
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 5%-palladium/activated carbon; hydrogen / methanol / 24 h / 20 °C
2.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C
2.2: 20 °C
With
5%-palladium/activated carbon; hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1002/chem.201101413
