C₅₉H₅₅O₂₀P

Base Information

• Chemical Name: C₅₉H₅₅O₂₀P
• CAS No.: 363619-60-7
• Molecular Formula: C₅₉H₅₅O₂₀P
• Molecular Weight: 1115.05
• Mol file: 363619-60-7.mol

Synonyms:C₅₉H₅₅O₂₀P

Chemical Property of C₅₉H₅₅O₂₀P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₉H₅₅O₂₀P

There total 23 articles about C₅₉H₅₅O₂₀P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,6-di-O-acetyl-2,3,4-tri-O-benzyl-α/β-D-galactopyranose (61277-56-3) → C59H55O20P (363619-60-7)

Guidance literature:

Multi-step reaction with 7 steps

1.1: H₂ / Pd(OH)2/C / methanol

2.1: pyridine

3.1: 85 percent / HBr / acetic acid; acetic anhydride; CH₂Cl₂

4.1: Ag₂CO₃ / acetone; H₂O

4.2: 85 percent / DBU / CH₂Cl₂

5.1: TMSOTf; 4 Angstroem MS_. / CH₂Cl₂ / 2 h / -30 °C

6.1: C₅H₅N*HClO₄ / nitromethane; methanol / 8 h / 65 °C

7.1: DMAP / pyridine

With dmap; trimethylsilyl trifluoromethanesulfonate; 4 Angstroem MS; hydrogen bromide; hydrogen; pyridinium perchlorate; silver carbonate; palladium dihydroxide; In pyridine; methanol; nitromethane; dichloromethane; water; acetic anhydride; acetic acid; acetone;

DOI:10.1016/S0040-4039(01)00961-3

Reference yield:

allyl α-D-mannopyranoside (41308-76-3,821794-45-0) → C59H55O20P (363619-60-7)

Guidance literature:

Multi-step reaction with 10 steps

1.1: 90 percent / TsOH*H₂O / acetone

2.1: AcOH; H₂O / 12 h / 0 °C

3.1: NaH / dimethylformamide / 2 h

4.1: KOBu-t / dimethylsulfoxide / 1 h / 60 °C

4.2: Hg(OAc)2 / tetrahydrofuran; H₂O / 0.33 h

5.1: 85 percent / LiHMDS / tetrahydrofuran / 55 °C

6.1: AcOH / H₂O / 3 h / 60 °C

7.1: pyridine

8.1: H₂ / Pd(OH)2/C / methanol

9.1: Et₃N / acetonitrile; CH₂Cl₂ / 0.5 h / -30 °C

10.1: TMSOTf; 4 Angstroem MS_. / CH₂Cl₂ / 2 h / -30 °C

With trimethylsilyl trifluoromethanesulfonate; 4 Angstroem MS; potassium tert-butylate; water; hydrogen; sodium hydride; acetic acid; triethylamine; lithium hexamethyldisilazane; palladium dihydroxide; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone; acetonitrile;

DOI:10.1016/S0040-4039(01)00961-3

Reference yield:

allyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside (119111-31-8) → C59H55O20P (363619-60-7)

Guidance literature:

Multi-step reaction with 11 steps

1.1: 94 percent / MeONa / methanol

2.1: 90 percent / TsOH*H₂O / acetone

3.1: AcOH; H₂O / 12 h / 0 °C

4.1: NaH / dimethylformamide / 2 h

5.1: KOBu-t / dimethylsulfoxide / 1 h / 60 °C

5.2: Hg(OAc)2 / tetrahydrofuran; H₂O / 0.33 h

6.1: 85 percent / LiHMDS / tetrahydrofuran / 55 °C

7.1: AcOH / H₂O / 3 h / 60 °C

8.1: pyridine

9.1: H₂ / Pd(OH)2/C / methanol

10.1: Et₃N / acetonitrile; CH₂Cl₂ / 0.5 h / -30 °C

11.1: TMSOTf; 4 Angstroem MS_. / CH₂Cl₂ / 2 h / -30 °C

With trimethylsilyl trifluoromethanesulfonate; 4 Angstroem MS; potassium tert-butylate; water; hydrogen; sodium hydride; acetic acid; triethylamine; lithium hexamethyldisilazane; palladium dihydroxide; sodium methylate; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone; acetonitrile;

DOI:10.1016/S0040-4039(01)00961-3

upstream raw materials:

benzoyl chloride

C₃₀H₃₁O₁₁P

6-O-acetyl-2,3,4-tri-O-benzoyl-α-D-galactopyranosyl trichloroacetimidate

benzoyl cyanide

Downstream raw materials:

C₅₇H₅₁O₂₀P

C₅₇H₅₃O₁₉P