Technology Process of C15H16(2)HNO3
There total 9 articles about C15H16(2)HNO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
deuteromethanol; triethylamine;
In
toluene;
at 20 ℃;
DOI:10.1021/ja412996f
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: triethylamine; magnesium chloride / benzene / 1.5 h / Reflux
2.1: sodium hydride / tetrahydrofuran; paraffin oil / 0.5 h / 20 °C
2.2: 24 h
3.1: phosphorus pentachloride / 1 h / 60 °C / Inert atmosphere
4.1: hydrogenchloride / water / 2.5 h / Reflux
5.1: acetic anhydride / 2 h / 23 °C
6.1: 15 h / 80 °C
7.1: 1,2-dichloro-ethane; pyridine / dichloromethane / 24 h / 20 °C
8.1: triethylamine / tetrahydrofuran / 72 h / 23 °C
9.1: deuteromethanol; triethylamine / toluene / 20 °C
With
pyridine; hydrogenchloride; deuteromethanol; phosphorus pentachloride; acetic anhydride; sodium hydride; 1,2-dichloro-ethane; triethylamine; magnesium chloride;
In
tetrahydrofuran; dichloromethane; water; toluene; paraffin oil; benzene;
DOI:10.1021/ja412996f
- Guidance literature:
-
Multi-step reaction with 7 steps
1: phosphorus pentachloride / 1 h / 60 °C / Inert atmosphere
2: hydrogenchloride / water / 2.5 h / Reflux
3: acetic anhydride / 2 h / 23 °C
4: 15 h / 80 °C
5: 1,2-dichloro-ethane; pyridine / dichloromethane / 24 h / 20 °C
6: triethylamine / tetrahydrofuran / 72 h / 23 °C
7: deuteromethanol; triethylamine / toluene / 20 °C
With
pyridine; hydrogenchloride; deuteromethanol; phosphorus pentachloride; acetic anhydride; 1,2-dichloro-ethane; triethylamine;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1021/ja412996f
