β-apolignan

Base Information

• Chemical Name: β-apolignan
• CAS No.: 59108-61-1
• Molecular Formula: C₁₈H₁₄O₂
• Molecular Weight: 262.308
• Mol file: 59108-61-1.mol

Synonyms:β-apolignan

Chemical Property of β-apolignan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of β-apolignan

There total 6 articles about β-apolignan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3,4-bis(phenylmethylene)dihydro-2(3H)-furanone (121851-43-2) → β-apolignan (59108-61-1)

Guidance literature:

In N,N-dimethyl-formamide; Irradiation;

DOI:10.1248/cpb.40.2525

Reference yield:

dimethyl (E)-benzylidenesuccinate (65859-90-7) → β-apolignan (59108-61-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 80 percent / t-BuOK / 2-methyl-propan-2-ol / 3.5 h / Ambient temperature

2: 2.8 g / LiEt₃BH / tetrahydrofuran / 3 h / -10 - 0 °C

3: p-toluenesulfonic acid / benzene / 12 h / 50 °C

4: 85 percent / dimethylformamide / Irradiation

With potassium tert-butylate; lithium triethylborohydride; toluene-4-sulfonic acid; In tetrahydrofuran; N,N-dimethyl-formamide; tert-butyl alcohol; benzene;

DOI:10.1248/cpb.40.2525

Reference yield:

(2E,3E)-2-benzylidene-3-(methoxycarbonyl)-4-phenylbut-3-enoic acid (121851-40-9) → β-apolignan (59108-61-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.8 g / LiEt₃BH / tetrahydrofuran / 3 h / -10 - 0 °C

2: p-toluenesulfonic acid / benzene / 12 h / 50 °C

3: 85 percent / dimethylformamide / Irradiation

With lithium triethylborohydride; toluene-4-sulfonic acid; In tetrahydrofuran; N,N-dimethyl-formamide; benzene;

DOI:10.1248/cpb.40.2525

upstream raw materials:

3,4-bis(phenylmethylene)dihydro-2(3H)-furanone

dimethyl (E)-benzylidenesuccinate

(2E,3E)-2-benzylidene-3-(methoxycarbonyl)-4-phenylbut-3-enoic acid

benzaldehyde